Human gut organoids: A promising model to study virus infection and pathogenesis processes

I. Aknouch

Human gut organoids: A promising model to study virus infection and pathogenesis processes

I. Aknouch

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

Abstract

This thesis focuses on the need for a human physiological culture system to study viral infections. It highlights the limitations of using cell lines and animal models for understanding human virus-host interactions in the gut. The thesis specifically explores the dynamics of virus-host interactions involving enterovirus A71 (EV-A71) and severe acute respiratory syndrome coronavirus 2

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Amsterdam
Supervisors/Advisors	Pajkrt, Dasja, Supervisor Wolthers, Katja, Co-supervisor Stittelaar, Koert J., Supervisor, External person
Award date	11 Oct 2023
Publication status	Published - 2023

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https://hdl.handle.net/11245.1/21ffbd04-76c7-4917-8007-9b0c420724b5

Cite this

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title = "Human gut organoids: A promising model to study virus infection and pathogenesis processes",

abstract = "This thesis focuses on the need for a human physiological culture system to study viral infections. It highlights the limitations of using cell lines and animal models for understanding human virus-host interactions in the gut. The thesis specifically explores the dynamics of virus-host interactions involving enterovirus A71 (EV-A71) and severe acute respiratory syndrome coronavirus 2",

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AB - This thesis focuses on the need for a human physiological culture system to study viral infections. It highlights the limitations of using cell lines and animal models for understanding human virus-host interactions in the gut. The thesis specifically explores the dynamics of virus-host interactions involving enterovirus A71 (EV-A71) and severe acute respiratory syndrome coronavirus 2

M3 - Phd-Thesis - Research and graduation internal

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Human gut organoids: A promising model to study virus infection and pathogenesis processes

Abstract

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