Highly specific and potently activating V gamma 9V delta 2-T cell specific nanobodies for diagnostic and therapeutic applications

Renee C. G. de Bruin; Sinead M. Lougheed; Liza van der Kruk; Anita G. Stam; Erik Hooijberg; Rob C. Roovers; Paul M. P. van Bergen En Henegouwen; Henk M. W. Verheul; Tanja D. de Gruijl; Hans J. van der Vliet

doi:10.1016/j.clim.2016.06.012

Highly specific and potently activating V gamma 9V delta 2-T cell specific nanobodies for diagnostic and therapeutic applications

Renee C. G. de Bruin
, Sinead M. Lougheed
, Liza van der Kruk
, Anita G. Stam
, Erik Hooijberg
, Rob C. Roovers
, Paul M. P. van Bergen En Henegouwen
, Henk M. W. Verheul
, Tanja D. de Gruijl
, Hans J. van der Vliet

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	128-138
Journal	Clinical Immunology
Volume	169
DOIs	https://doi.org/10.1016/j.clim.2016.06.012
Publication status	Published - Aug 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Nanobody
Single-domain antibody fragment
VHH
Gamma delta T cells
Flow cytometry
MACS
Immunocytochemistry
Immunotherapy
Cancer

Access to Document

10.1016/j.clim.2016.06.012

Cite this

de Bruin, R. C. G., Lougheed, S. M., van der Kruk, L., Stam, A. G., Hooijberg, E., Roovers, R. C., Henegouwen, P. M. P. V. B. E., Verheul, H. M. W., de Gruijl, T. D., & van der Vliet, H. J. (2016). Highly specific and potently activating V gamma 9V delta 2-T cell specific nanobodies for diagnostic and therapeutic applications. Clinical Immunology, 169, 128-138. https://doi.org/10.1016/j.clim.2016.06.012

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title = "Highly specific and potently activating V gamma 9V delta 2-T cell specific nanobodies for diagnostic and therapeutic applications",

keywords = "Nanobody, Single-domain antibody fragment, VHH, Gamma delta T cells, Flow cytometry, MACS, Immunocytochemistry, Immunotherapy, Cancer",

author = "\{de Bruin\}, \{Renee C. G.\} and Lougheed, \{Sinead M.\} and \{van der Kruk\}, Liza and Stam, \{Anita G.\} and Erik Hooijberg and Roovers, \{Rob C.\} and Henegouwen, \{Paul M. P. van Bergen En\} and Verheul, \{Henk M. W.\} and \{de Gruijl\}, \{Tanja D.\} and \{van der Vliet\}, \{Hans J.\}",

year = "2016",

month = aug,

doi = "10.1016/j.clim.2016.06.012",

language = "English",

volume = "169",

pages = "128--138",

journal = "Clinical Immunology",

issn = "1521-6616",

publisher = "Academic Press Inc.",

}

de Bruin, RCG, Lougheed, SM, van der Kruk, L, Stam, AG, Hooijberg, E, Roovers, RC, Henegouwen, PMPVBE, Verheul, HMW, de Gruijl, TD & van der Vliet, HJ 2016, 'Highly specific and potently activating V gamma 9V delta 2-T cell specific nanobodies for diagnostic and therapeutic applications', Clinical Immunology, vol. 169, pp. 128-138. https://doi.org/10.1016/j.clim.2016.06.012

TY - JOUR

T1 - Highly specific and potently activating V gamma 9V delta 2-T cell specific nanobodies for diagnostic and therapeutic applications

AU - de Bruin, Renee C. G.

AU - Lougheed, Sinead M.

AU - van der Kruk, Liza

AU - Stam, Anita G.

AU - Hooijberg, Erik

AU - Roovers, Rob C.

AU - Henegouwen, Paul M. P. van Bergen En

AU - Verheul, Henk M. W.

AU - de Gruijl, Tanja D.

AU - van der Vliet, Hans J.

PY - 2016/8

Y1 - 2016/8

KW - Nanobody

KW - Single-domain antibody fragment

KW - VHH

KW - Gamma delta T cells

KW - Flow cytometry

KW - MACS

KW - Immunocytochemistry

KW - Immunotherapy

KW - Cancer

U2 - 10.1016/j.clim.2016.06.012

DO - 10.1016/j.clim.2016.06.012

M3 - Article

C2 - 27373969

SN - 1521-6616

VL - 169

SP - 128

EP - 138

JO - Clinical Immunology

JF - Clinical Immunology

ER -