Heart failure: advances through genomics

Esther E. Creemers; Arthur A. Wilde; Yigal M. Pinto

doi:10.1038/nrg2983

Heart failure: advances through genomics

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

Heart failure is an increasingly prevalent and highly lethal disease that is most often caused by underlying pathologies, such as myocardial infarction or hypertension, but it can also be the result of a single gene mutation. Comprehensive genetic and genomic approaches are starting to disentangle the diverse molecular underpinnings of both forms of the disease and promise to yield much-needed novel diagnostic and therapeutic options for specific subtypes of heart failure

Original language	English
Pages (from-to)	357-362
Journal	Nature reviews. Genetics
Volume	12
Issue number	5
DOIs	https://doi.org/10.1038/nrg2983
Publication status	Published - 2011

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1038/nrg2983

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title = "Heart failure: advances through genomics",

abstract = "Heart failure is an increasingly prevalent and highly lethal disease that is most often caused by underlying pathologies, such as myocardial infarction or hypertension, but it can also be the result of a single gene mutation. Comprehensive genetic and genomic approaches are starting to disentangle the diverse molecular underpinnings of both forms of the disease and promise to yield much-needed novel diagnostic and therapeutic options for specific subtypes of heart failure",

author = "Creemers, \{Esther E.\} and Wilde, \{Arthur A.\} and Pinto, \{Yigal M.\}",

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AU - Wilde, Arthur A.

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AB - Heart failure is an increasingly prevalent and highly lethal disease that is most often caused by underlying pathologies, such as myocardial infarction or hypertension, but it can also be the result of a single gene mutation. Comprehensive genetic and genomic approaches are starting to disentangle the diverse molecular underpinnings of both forms of the disease and promise to yield much-needed novel diagnostic and therapeutic options for specific subtypes of heart failure

U2 - 10.1038/nrg2983

DO - 10.1038/nrg2983

M3 - Review article

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EP - 362

JO - Nature reviews. Genetics

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Heart failure: advances through genomics

Abstract

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