Functions and biosynthesis of plasmalogens in health and disease

P. Brites; H. R. Waterham; R. J. A. Wanders

doi:10.1016/j.bbalip.2003.12.010

Functions and biosynthesis of plasmalogens in health and disease

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

Plasmalogens (1-O-alk-1'-enyl-2-acyl glycerophospholipids) constitute a special class of phospholipids characterized by the presence of a vinyl-ether bond at the sn-1 position. Although long considered as biological peculiarities, interest in this group of phospholipids has grown in recent years, thanks to the realization that plasmalogens are involved in different human diseases. In this review, we summarize the current state of knowledge with respect to the enzymatic synthesis of plasmalogens, the characteristic topology of the enzymes involved and the biological roles that have been assigned to plasmalogens. (C) 2004 Elsevier B.V All rights reserved

Original language	English
Pages (from-to)	219-231
Journal	BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
Volume	1636
Issue number	2-3
DOIs	https://doi.org/10.1016/j.bbalip.2003.12.010
Publication status	Published - 2004

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1016/j.bbalip.2003.12.010

Cite this

@article{3e93bdc0387841edb09c0b6a45d5f8b3,

title = "Functions and biosynthesis of plasmalogens in health and disease",

abstract = "Plasmalogens (1-O-alk-1'-enyl-2-acyl glycerophospholipids) constitute a special class of phospholipids characterized by the presence of a vinyl-ether bond at the sn-1 position. Although long considered as biological peculiarities, interest in this group of phospholipids has grown in recent years, thanks to the realization that plasmalogens are involved in different human diseases. In this review, we summarize the current state of knowledge with respect to the enzymatic synthesis of plasmalogens, the characteristic topology of the enzymes involved and the biological roles that have been assigned to plasmalogens. (C) 2004 Elsevier B.V All rights reserved",

author = "P. Brites and Waterham, \{H. R.\} and Wanders, \{R. J. A.\}",

year = "2004",

doi = "10.1016/j.bbalip.2003.12.010",

language = "English",

volume = "1636",

pages = "219--231",

journal = "BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS",

issn = "1388-1981",

publisher = "Elsevier",

number = "2-3",

}

TY - JOUR

T1 - Functions and biosynthesis of plasmalogens in health and disease

AU - Brites, P.

AU - Waterham, H. R.

AU - Wanders, R. J. A.

PY - 2004

Y1 - 2004

N2 - Plasmalogens (1-O-alk-1'-enyl-2-acyl glycerophospholipids) constitute a special class of phospholipids characterized by the presence of a vinyl-ether bond at the sn-1 position. Although long considered as biological peculiarities, interest in this group of phospholipids has grown in recent years, thanks to the realization that plasmalogens are involved in different human diseases. In this review, we summarize the current state of knowledge with respect to the enzymatic synthesis of plasmalogens, the characteristic topology of the enzymes involved and the biological roles that have been assigned to plasmalogens. (C) 2004 Elsevier B.V All rights reserved

AB - Plasmalogens (1-O-alk-1'-enyl-2-acyl glycerophospholipids) constitute a special class of phospholipids characterized by the presence of a vinyl-ether bond at the sn-1 position. Although long considered as biological peculiarities, interest in this group of phospholipids has grown in recent years, thanks to the realization that plasmalogens are involved in different human diseases. In this review, we summarize the current state of knowledge with respect to the enzymatic synthesis of plasmalogens, the characteristic topology of the enzymes involved and the biological roles that have been assigned to plasmalogens. (C) 2004 Elsevier B.V All rights reserved

U2 - 10.1016/j.bbalip.2003.12.010

DO - 10.1016/j.bbalip.2003.12.010

M3 - Review article

C2 - 15164770

SN - 1388-1981

VL - 1636

SP - 219

EP - 231

JO - BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

JF - BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

IS - 2-3

ER -

Functions and biosynthesis of plasmalogens in health and disease

Abstract

UN SDGs

Access to Document

Fingerprint

Cite this