Four-year outcome after early withdrawal of antiepileptic drugs in childhood epilepsy

A. T. Geerts; J. M. F. Niermeijer; A. C. B. Peters; W. F. M. Arts; O. F. Brouwer; H. Stroink; E. A. J. Peeters; C. A. van Donselaar

doi:10.1212/01.WNL.0000166035.26217.61

Four-year outcome after early withdrawal of antiepileptic drugs in childhood epilepsy

A. T. Geerts
, J. M. F. Niermeijer
, A. C. B. Peters
, W. F. M. Arts
, O. F. Brouwer
, H. Stroink
, E. A. J. Peeters
, C. A. van Donselaar^*

^*Corresponding author for this work

Erasmus University Rotterdam
Utrecht University
University of Groningen, University Medical Center Groningen
Department of Medical Oncology, Elisabeth-Tweesteden Hospital, Tilburg, The Netherlands
Haaglanden Medisch Centrum

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Four-year follow-up of children with epilepsy included in a randomized trial of early withdrawal of antiepileptic drugs showed that 51% achieved a terminal remission of at least 2 years without medication and 21% with medication; 15% had seizures during the fourth year. Early medication withdrawal is not recommended as standard practice in children with a rapid response to medication. The authors developed a model to predict outcome if withdrawal is considered. Copyright © 2005 by AAN Enterprises, Inc.

Original language	English
Pages (from-to)	2136-2138
Journal	Neurology
Volume	64
Issue number	12
DOIs	https://doi.org/10.1212/01.WNL.0000166035.26217.61
Publication status	Published - 28 Jun 2005
Externally published	Yes

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title = "Four-year outcome after early withdrawal of antiepileptic drugs in childhood epilepsy",

abstract = "Four-year follow-up of children with epilepsy included in a randomized trial of early withdrawal of antiepileptic drugs showed that 51\% achieved a terminal remission of at least 2 years without medication and 21\% with medication; 15\% had seizures during the fourth year. Early medication withdrawal is not recommended as standard practice in children with a rapid response to medication. The authors developed a model to predict outcome if withdrawal is considered. Copyright {\textcopyright} 2005 by AAN Enterprises, Inc.",

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AU - Geerts, A. T.

AU - Niermeijer, J. M. F.

AU - Peters, A. C. B.

AU - Arts, W. F. M.

AU - Brouwer, O. F.

AU - Stroink, H.

AU - Peeters, E. A. J.

AU - van Donselaar, C. A.

PY - 2005/6/28

Y1 - 2005/6/28

N2 - Four-year follow-up of children with epilepsy included in a randomized trial of early withdrawal of antiepileptic drugs showed that 51% achieved a terminal remission of at least 2 years without medication and 21% with medication; 15% had seizures during the fourth year. Early medication withdrawal is not recommended as standard practice in children with a rapid response to medication. The authors developed a model to predict outcome if withdrawal is considered. Copyright © 2005 by AAN Enterprises, Inc.

AB - Four-year follow-up of children with epilepsy included in a randomized trial of early withdrawal of antiepileptic drugs showed that 51% achieved a terminal remission of at least 2 years without medication and 21% with medication; 15% had seizures during the fourth year. Early medication withdrawal is not recommended as standard practice in children with a rapid response to medication. The authors developed a model to predict outcome if withdrawal is considered. Copyright © 2005 by AAN Enterprises, Inc.

UR - https://www.scopus.com/pages/publications/21144452601

UR - https://www.ncbi.nlm.nih.gov/pubmed/15985589

U2 - 10.1212/01.WNL.0000166035.26217.61

DO - 10.1212/01.WNL.0000166035.26217.61

M3 - Article

C2 - 15985589

SN - 0028-3878

VL - 64

SP - 2136

EP - 2138

JO - Neurology

JF - Neurology

IS - 12

ER -

Four-year outcome after early withdrawal of antiepileptic drugs in childhood epilepsy

Abstract

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