Evidence that leukocyte function-associated antigen-1 is involved in recirculation and homing of human lymphocytes via high endothelial venules

S. T. Pals; A. den Otter; F. Miedema; P. Kabel; G. D. Keizer; R. J. Scheper; C. J. Meijer

Evidence that leukocyte function-associated antigen-1 is involved in recirculation and homing of human lymphocytes via high endothelial venules

S. T. Pals
, A. den Otter
, F. Miedema
, P. Kabel
, G. D. Keizer
, R. J. Scheper
, C. J. Meijer

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

We report the results of mAb inhibition studies of human lymphocyte-high endothelial venule interaction in vitro. These studies in which T cells from both normal donors and from a LFA-1-deficient patient were used indicate that in addition to a system of organ-specific 90-kDa "homing" receptors on lymphocytes, LFA-1 is also involved in lymphocyte recirculation and homing

Original language	English
Pages (from-to)	1851-1853
Journal	Journal of immunology (Baltimore, Md.
Volume	140
Issue number	6
Publication status	Published - 1988

Cite this

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title = "Evidence that leukocyte function-associated antigen-1 is involved in recirculation and homing of human lymphocytes via high endothelial venules",

abstract = "We report the results of mAb inhibition studies of human lymphocyte-high endothelial venule interaction in vitro. These studies in which T cells from both normal donors and from a LFA-1-deficient patient were used indicate that in addition to a system of organ-specific 90-kDa {"}homing{"} receptors on lymphocytes, LFA-1 is also involved in lymphocyte recirculation and homing",

author = "Pals, \{S. T.\} and \{den Otter\}, A. and F. Miedema and P. Kabel and Keizer, \{G. D.\} and Scheper, \{R. J.\} and Meijer, \{C. J.\}",

year = "1988",

language = "English",

volume = "140",

pages = "1851--1853",

journal = "Journal of immunology (Baltimore, Md.",

issn = "0022-1767",

publisher = "American Association of Immunologists",

number = "6",

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TY - JOUR

T1 - Evidence that leukocyte function-associated antigen-1 is involved in recirculation and homing of human lymphocytes via high endothelial venules

AU - Pals, S. T.

AU - den Otter, A.

AU - Miedema, F.

AU - Kabel, P.

AU - Keizer, G. D.

AU - Scheper, R. J.

AU - Meijer, C. J.

PY - 1988

Y1 - 1988

N2 - We report the results of mAb inhibition studies of human lymphocyte-high endothelial venule interaction in vitro. These studies in which T cells from both normal donors and from a LFA-1-deficient patient were used indicate that in addition to a system of organ-specific 90-kDa "homing" receptors on lymphocytes, LFA-1 is also involved in lymphocyte recirculation and homing

AB - We report the results of mAb inhibition studies of human lymphocyte-high endothelial venule interaction in vitro. These studies in which T cells from both normal donors and from a LFA-1-deficient patient were used indicate that in addition to a system of organ-specific 90-kDa "homing" receptors on lymphocytes, LFA-1 is also involved in lymphocyte recirculation and homing

M3 - Article

C2 - 3279123

SN - 0022-1767

VL - 140

SP - 1851

EP - 1853

JO - Journal of immunology (Baltimore, Md.

JF - Journal of immunology (Baltimore, Md.

IS - 6

ER -

Evidence that leukocyte function-associated antigen-1 is involved in recirculation and homing of human lymphocytes via high endothelial venules

Abstract

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