@article{4a782624f8304ed09e9436d49f09511c,
title = "Einthoven Dissertation Prizes 2023",
author = "Piek, \{J. J.\}",
note = "Funding Information: Using this biological principle, we designed an international clinical trial in which patients with chronic coronary syndromes were randomised to low-dose colchicine (0.5 mg once daily) or placebo. We recruited at outpatient clinics, without any preselection on inflammatory profile and irrespective of the baseline cardiovascular risk. The primary outcome was cardiovascular death, myocardial infarction, ischaemic stroke, or ischaemia-driven coronary revascularisation. The trial was conducted in 30 Dutch and 13 Australian hospitals. The trial was investigator-initiated and sponsored by the Netherlands Organisation for Health Research and Development (ZonMW). By employing risk-based monitoring strategies, innovative trial medication dispensing and following large in-kind contributions from the participating cardiology centres, the costs of the trial were kept to less than a tenth of equivalent industry-sponsored trials.",
year = "2023",
month = sep,
doi = "10.1007/s12471-023-01803-1",
language = "English",
volume = "31",
pages = "357--359",
journal = "Netherlands heart journal",
issn = "1568-5888",
publisher = "Bohn Stafleu Van Loghum",
number = "9",
}