Effectiveness and toxicity of single-fraction radiotherapy with 1 X 8 Gy for metastatic spinal cord compression

Dirk Rades; Lukas J. A. Stalpers; Maarten C. C. M. Hulshof; Oliver Zschenker; Winfried Alberti; Caro C. E. Koning

doi:10.1016/j.radonc.2004.12.013

Effectiveness and toxicity of single-fraction radiotherapy with 1 X 8 Gy for metastatic spinal cord compression

Dirk Rades
, Lukas J. A. Stalpers
, Maarten C. C. M. Hulshof
, Oliver Zschenker
, Winfried Alberti
, Caro C. E. Koning

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Toxicity and functional. outcome were evaluated in 199 MSCC-patients irradiated with 1 X 8 Gy. Motor function improved in 54/199 patients (27%). Patients who regained walking ability were 20/78 (26%). Long-term-survivors (>= 12 months) who needed re-irradiation for in-field-recurrence were 19/65 (29%). Acute toxicity was mild, late toxicity not observed. A randomised trial comparing single-fraction RT to multi-fraction RT is mandatory. (c) 2005 Elsevier Ireland Ltd. All rights reserved

Original language	English
Pages (from-to)	70-73
Journal	Radiotherapy and oncology
Volume	75
Issue number	1
DOIs	https://doi.org/10.1016/j.radonc.2004.12.013
Publication status	Published - 2005

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title = "Effectiveness and toxicity of single-fraction radiotherapy with 1 X 8 Gy for metastatic spinal cord compression",

abstract = "Toxicity and functional. outcome were evaluated in 199 MSCC-patients irradiated with 1 X 8 Gy. Motor function improved in 54/199 patients (27\%). Patients who regained walking ability were 20/78 (26\%). Long-term-survivors (>= 12 months) who needed re-irradiation for in-field-recurrence were 19/65 (29\%). Acute toxicity was mild, late toxicity not observed. A randomised trial comparing single-fraction RT to multi-fraction RT is mandatory. (c) 2005 Elsevier Ireland Ltd. All rights reserved",

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AU - Rades, Dirk

AU - Stalpers, Lukas J. A.

AU - Hulshof, Maarten C. C. M.

AU - Zschenker, Oliver

AU - Alberti, Winfried

AU - Koning, Caro C. E.

PY - 2005

Y1 - 2005

N2 - Toxicity and functional. outcome were evaluated in 199 MSCC-patients irradiated with 1 X 8 Gy. Motor function improved in 54/199 patients (27%). Patients who regained walking ability were 20/78 (26%). Long-term-survivors (>= 12 months) who needed re-irradiation for in-field-recurrence were 19/65 (29%). Acute toxicity was mild, late toxicity not observed. A randomised trial comparing single-fraction RT to multi-fraction RT is mandatory. (c) 2005 Elsevier Ireland Ltd. All rights reserved

AB - Toxicity and functional. outcome were evaluated in 199 MSCC-patients irradiated with 1 X 8 Gy. Motor function improved in 54/199 patients (27%). Patients who regained walking ability were 20/78 (26%). Long-term-survivors (>= 12 months) who needed re-irradiation for in-field-recurrence were 19/65 (29%). Acute toxicity was mild, late toxicity not observed. A randomised trial comparing single-fraction RT to multi-fraction RT is mandatory. (c) 2005 Elsevier Ireland Ltd. All rights reserved

U2 - 10.1016/j.radonc.2004.12.013

DO - 10.1016/j.radonc.2004.12.013

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EP - 73

JO - Radiotherapy and oncology

JF - Radiotherapy and oncology

IS - 1

ER -

Effectiveness and toxicity of single-fraction radiotherapy with 1 X 8 Gy for metastatic spinal cord compression

Abstract

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