Do not CROSSlink with DNA damage tolerance

R.A. Shah

Do not CROSSlink with DNA damage tolerance

R.A. Shah

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

Abstract

The DNA Damage Tolerance (DDT) system enables a continuation of DNA synthesis in the presence of a plethora of DNA lesions. The most studied mode of DDT is Translesion synthesis (TLS) which takes advantage of specialized damage-tolerant TLS polymerases to enable a direct bypass of a replication impediment. TLS provides an essential repair intermediate step within the

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Amsterdam
Supervisors/Advisors	van Leeuwen, Fred, Supervisor Jacobs, Heinz, Co-supervisor, External person
Award date	27 Oct 2023
Print ISBNs	9789464199239
Publication status	Published - 2023

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M3 - Phd-Thesis - Research and graduation internal

SN - 9789464199239

ER -

Do not CROSSlink with DNA damage tolerance

Abstract

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