Discovery of a γ-carboxyglutamic acid-containing protein in human spermatozoa

Berry A M Soute; Werner Müller-Esterl; Marian A G de Boer-van den Berg; Magda Ulrich; Cees Vermeer

doi:10.1016/0014-5793(85)80444-0

Discovery of a γ-carboxyglutamic acid-containing protein in human spermatozoa

Berry A M Soute^*
, Werner Müller-Esterl
, Marian A G de Boer-van den Berg
, Magda Ulrich
, Cees Vermeer

^*Corresponding author for this work

University of Limburg
Maastricht University

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Here we describe the identification of a γ-carboxyglutamic acid-containing protein in human spermatozoa. After thermal decarboxylation the protein is a good substrate for vitamin K-dependent carboxylase from various origins. A quick purification procedure for the decarboxylated protein is presented and in a preliminary characterization we have established its M_r, (28000-30000) and its amino acid composition.

Original language	English
Pages (from-to)	137-141
Number of pages	5
Journal	FEBS letters
Volume	190
Issue number	1
DOIs	https://doi.org/10.1016/0014-5793(85)80444-0
Publication status	Published - 7 Oct 1985

Keywords

Carboxylase
Sperm
Vitamin K
Warfarin
γ-Carboxyglutamic acid

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10.1016/0014-5793(85)80444-0

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abstract = "Here we describe the identification of a γ-carboxyglutamic acid-containing protein in human spermatozoa. After thermal decarboxylation the protein is a good substrate for vitamin K-dependent carboxylase from various origins. A quick purification procedure for the decarboxylated protein is presented and in a preliminary characterization we have established its Mr, (28000-30000) and its amino acid composition.",

keywords = "Carboxylase, Sperm, Vitamin K, Warfarin, γ-Carboxyglutamic acid",

author = "Soute, \{Berry A M\} and Werner M{\"u}ller-Esterl and \{de Boer-van den Berg\}, \{Marian A G\} and Magda Ulrich and Cees Vermeer",

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AU - Soute, Berry A M

AU - Müller-Esterl, Werner

AU - de Boer-van den Berg, Marian A G

AU - Ulrich, Magda

AU - Vermeer, Cees

PY - 1985/10/7

Y1 - 1985/10/7

N2 - Here we describe the identification of a γ-carboxyglutamic acid-containing protein in human spermatozoa. After thermal decarboxylation the protein is a good substrate for vitamin K-dependent carboxylase from various origins. A quick purification procedure for the decarboxylated protein is presented and in a preliminary characterization we have established its Mr, (28000-30000) and its amino acid composition.

AB - Here we describe the identification of a γ-carboxyglutamic acid-containing protein in human spermatozoa. After thermal decarboxylation the protein is a good substrate for vitamin K-dependent carboxylase from various origins. A quick purification procedure for the decarboxylated protein is presented and in a preliminary characterization we have established its Mr, (28000-30000) and its amino acid composition.

KW - Carboxylase

KW - Sperm

KW - Vitamin K

KW - Warfarin

KW - γ-Carboxyglutamic acid

UR - https://www.scopus.com/pages/publications/0022249125

U2 - 10.1016/0014-5793(85)80444-0

DO - 10.1016/0014-5793(85)80444-0

M3 - Article

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SP - 137

EP - 141

JO - FEBS letters

JF - FEBS letters

IS - 1

ER -

Discovery of a γ-carboxyglutamic acid-containing protein in human spermatozoa

Abstract

Keywords

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