Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity: The ARIA-MASK-air? approach

Jean Bousquet; Josep M. Anto; Bernardo Sousa-Pinto; Wienczyslawa Czarlewski; Anna Bedbrook; Tari Haahtela; Ludger Klimek; Oliver Pfaar; Piotr Kuna; Maciej Kupczyk; Frederico S. Regateiro; Boleslaw Samolinski; Arunas Valiulis; Arzu Yorgancioglu; Sylvie Arnavielhe; Xavier Basaga?a; Karl C. Bergmann; Sinthia Bosnic-Anticevich; Luisa Brussino; G. Walter Canonica; Victoria Cardona; Lorenzo Cecchi; Claudia Chaves-Loureiro; Elisio Costa; Alvaro A. Cruz; Bilun Gemicioglu; Wytske J. Fokkens; Juan Carlos Ivancevich; Helga Kraxner; Violeta Kvedariene; D. sir?e E. Larenas-Linnemann; Daniel Laune; Renaud Louis; Michael Makris; Marcus Maurer; Erik Mel?n; Yann Micheli; Mario Morais-Almeida; Joaquim Mullol; Marek Niedoszytko; Yoshitaka Okamoto; Nikolaos G. Papadopoulos; Vincenzo Patella; Nh?n Pham-Thi; Philip W. Rouadi; Joaquin Sastre; Nicola Scichilone; Aziz Sheikh; Mikhail Sofiev; Luis Taborda-Barata; Sanna Toppila-Salmi; Ioanna Tsiligianni; Erkka Valovirta; Maria Teresa Ventura; Rafael Jos? Vieira; Mihaela Zidarn; Rita Amaral; Ignacio J. Ansotegui; Annabelle B?dard; Samuel Benveniste; Michael Bewick; Carsten Bindslev-Jensen; Hubert Blain; Matteo Bonini; Rodolphe Bourret; Fulvio Braido; Pedro Carreiro-Martins; Denis Charpin; Ivan Cherrez-Ojeda; Tomas Chivato; Derek K. Chu; Cemal Cingi; Stefano del Giacco; Fr?d?ric de Blay; Philippe Devillier; Govert de Vries; Maria Doulaptsi; Virginie Doyen; G. rard Dray; Jean-Fran?ois Fontaine; R. Maximiliano Gomez; Jan Hagemann; Enrico Heffler; Maja Hofmann; Ewa Jassem; Marek Jutel; Thomas Keil; Vicky Kritikos; Inger Kull; Marek Kulus; Olga Louren?o; Eve Mathieu-Dupas; Enrica Menditto; Ralph M?sges; Ruth Murray; Rachel Nadif; Hugo Neffen; Stefania Nicola; Robyn O?Hehir; Heidi Olze; Yuliia Palamarchuk; Jean-Louis P?pin; Benoit P?tr?; Robert Picard; Constantinos Pitsios; Francesca Puggioni; Santiago Quirce; Filip Raciborski; Sietze Reitsma; Nicolas Roche; Monica Rodriguez-Gonzalez; Jan Romantowski; Ana S?-Sousa; Faradiba S. Serpa; Marine Savour?; Mohamed H. Shamji; Milan Sova; Annette Sperl; Cristiana Stellato; Ana Todo-Bom; Peter Valentin Tomazic; Olivier Vandenplas; Michiel van Eerd; Tuula Vasankari; Fr?d?ric Viart; Susan Waserman; Joao A. Fonseca; Torsten Zuberbier

doi:10.1002/clt2.12215

Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity: The ARIA-MASK-air? approach

Jean Bousquet^*
, Josep M. Anto
, Bernardo Sousa-Pinto
, Wienczyslawa Czarlewski
, Anna Bedbrook
, Tari Haahtela
, Ludger Klimek
, Oliver Pfaar
, Piotr Kuna
, Maciej Kupczyk
, Frederico S. Regateiro
, Boleslaw Samolinski
, Arunas Valiulis
, Arzu Yorgancioglu
, Sylvie Arnavielhe
, Xavier Basaga?a
, Karl C. Bergmann
, Sinthia Bosnic-Anticevich
, Luisa Brussino
, G. Walter Canonica

Victoria Cardona, Lorenzo Cecchi, Claudia Chaves-Loureiro, Elisio Costa, Alvaro A. Cruz, Bilun Gemicioglu, Wytske J. Fokkens, Juan Carlos Ivancevich, Helga Kraxner, Violeta Kvedariene, D. sir?e E. Larenas-Linnemann, Daniel Laune, Renaud Louis, Michael Makris, Marcus Maurer, Erik Mel?n, Yann Micheli, Mario Morais-Almeida, Joaquim Mullol, Marek Niedoszytko, Yoshitaka Okamoto, Nikolaos G. Papadopoulos, Vincenzo Patella, Nh?n Pham-Thi, Philip W. Rouadi, Joaquin Sastre, Nicola Scichilone, Aziz Sheikh, Mikhail Sofiev, Luis Taborda-Barata, Sanna Toppila-Salmi, Ioanna Tsiligianni, Erkka Valovirta, Maria Teresa Ventura, Rafael Jos? Vieira, Mihaela Zidarn, Rita Amaral, Ignacio J. Ansotegui, Annabelle B?dard, Samuel Benveniste, Michael Bewick, Carsten Bindslev-Jensen, Hubert Blain, Matteo Bonini, Rodolphe Bourret, Fulvio Braido, Pedro Carreiro-Martins, Denis Charpin, Ivan Cherrez-Ojeda, Tomas Chivato, Derek K. Chu, Cemal Cingi, Stefano del Giacco, Fr?d?ric de Blay, Philippe Devillier, Govert de Vries, Maria Doulaptsi, Virginie Doyen, G. rard Dray, Jean-Fran?ois Fontaine, R. Maximiliano Gomez, Jan Hagemann, Enrico Heffler, Maja Hofmann, Ewa Jassem, Marek Jutel, Thomas Keil, Vicky Kritikos, Inger Kull, Marek Kulus, Olga Louren?o, Eve Mathieu-Dupas, Enrica Menditto, Ralph M?sges, Ruth Murray, Rachel Nadif, Hugo Neffen, Stefania Nicola, Robyn O?Hehir, Heidi Olze, Yuliia Palamarchuk, Jean-Louis P?pin, Benoit P?tr?, Robert Picard, Constantinos Pitsios, Francesca Puggioni, Santiago Quirce, Filip Raciborski, Sietze Reitsma, Nicolas Roche, Monica Rodriguez-Gonzalez, Jan Romantowski, Ana S?-Sousa, Faradiba S. Serpa, Marine Savour?, Mohamed H. Shamji, Milan Sova, Annette Sperl, Cristiana Stellato, Ana Todo-Bom, Peter Valentin Tomazic, Olivier Vandenplas, Michiel van Eerd, Tuula Vasankari, Fr?d?ric Viart, Susan Waserman, Joao A. Fonseca, Torsten Zuberbier

^*Corresponding author for this work

Affiliatie UvA

Charité – Universitätsmedizin Berlin
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
Lapeyronie - CHU of Montpellier, France
Université Paris-Sud
Barcelona Institute for Global Health
Pompeu Fabra University
CIBER Epidemiología y Salud Pública (CIBERESP)
University of Porto
Conseil médical Czarlewski, Levallois, France
MASK-Air, Montpellier, France
Hospital District of Helsinki and Uusimaa
Johannes Gutenberg University Mainz
Center of Rhinology and Allergology, An den Quellen 10, 65183, Wiesbaden, Germany
Universitätsklinikum Giessen und Marburg, Standort Marburg
Medical University of Łódź
University of Coimbra
Medical University of Warsaw
Institute of Clinical Medicine and Institute of Health Sciences
Vilnius University
Manisa Celal Bayar University
GRADeS Occitanie
The University of Sydney
Woolcock Emphysema Centre and Sydney Local Health District, Glebe, New South Wales, Australia
University of Turin
Ospedale Mauriziano Umberto I
Humanitas University
IRCCS Istituto Clinico Humanitas - Rozzano (Milano)
Autonomous University of Barcelona
ARADyAL Research Network
SOS Allergology and Clinical Immunology, USL Toscana Centro, Prato, Italy
Universidade Federal da Bahia
Istanbul University - Cerrahpaşa, Cerrahpaşa School of Medicine, Istanbul, 34320, Turkey
Clinica Santa Isabel
Semmelweis University
Médica Sur Clinical Foundation and Hospital
KYomed INNOV
University of Liege
National and Kapodistrian University of Athens
Karolinska Institutet
Hospital CUF-Descobertas
University of Barcelona
Medical University of Gdańsk
Chiba University
Chiba Rosai Hospital
Division of Allergy and Clinical Immunology, Department of Medicine, Agency of Health ASL Salerno, "Santa Maria della Speranza" Hospital, Battipaglia, Salerno, Italy
Agency of Health ASL
Ecole Polytechnique Palaiseau, IRBA (Institut de Recherche bio-Médicale des Armées), Bretigny, France
Department of Otolaryngology-Head and Neck Surgery, Eye and Ear University Hospital, Beirut, Lebanon
Dar Al-Shifa Hospital
Universidad Autónoma de Madrid
University of Palermo
University of Edinburgh
Finnish Meteorological Institute
Department of Immunoallergology, Covilhã, Portugal
University of Beira Interior
International Primary Care Respiratory Group, Aberdeen, United Kingdom
University of Crete
University of Turku
Terveystalo Allergy Clinic, Turku, Finland
University of Bari
University of Ljubljana
Department of Allergy and Immunology, Erandio, Spain
U1179 UVSQ-INSERM Handicap Neuromusculaire: Physiologie, France
APHP, Hôpital Broca, Paris, France
École des mines Paris
University of Central Lancashire
Research Center for Anaphylaxis (ORCA), Odense, Denmark
University of Southern Denmark
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Royal Brompton Hospital
Centre Hospitalier Valenciennes, Valenciennes, France
University of Genoa
San Martino Hospital Genoa
NOVA University Lisbon
University of Lisbon
Hôpital Nord AP-HM
Universidad Espíritu Santo, Ecuador
Respiralab Research Group
CEU Universities
McMaster University
Osmangazi University
University Hospital of Cagliari
Université de Strasbourg
Université Paris-Saclay
Peercode BV, Geldermalsen, The Netherlands
Heraklion University Hospital
CHU UCL Namur
Université catholique de Louvain
IMT Mines Alès
Allergist, Reims, France
Universidad Catolica de Salta
Berlin Institute of Health, Comprehensive Allergy Center, Department of Dermatology and Allergy, Berlin
Wrocław Medical University
ALL-MED Medical Research Institute, Breslau, Polen
University of Würzburg
Bavarian Health and Food Safety Authority
University of Naples Federico II
CRI - Clinical Research International Ltd., Hamburg
Medscript Ltd
OPC
Director of Center of Allergy, Immunology and Respiratory Diseases, Santa Fe, Argentina
Monash University
Université Grenoble Alpes
Institut national de la santé et de la recherche médicale
Conseil Général de l'Economie Ministère de l'Economie, de l'Industrie et du Numérique, Paris, France
University of Cyprus Medical School, Nicosia, Cyprus
Assistance publique – Hôpitaux de Paris
Université Paris 5
Spanish Hospital, Mexico City
Asthma Reference Center - School of Medicine of Santa Casa de Miseric?rdia of Vit?ria
Imperial College London
National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK
Masaryk University
University of Salerno
LKH-Universitätsklinikum Graz
Fihla
ASA - Advanced Solutions Accelerator

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

MASK-air^®, a validated mHealth app (Medical Device regulation Class IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK-air^® is a Good Practice of DG Santé on digitally-enabled, patient-centred care. It is also a candidate Good Practice of OECD (Organisation for Economic Co-operation and Development). MASK-air^® data has enabled novel phenotype discovery and characterisation, as well as novel insights into the management of allergic rhinitis. MASK-air^® data show that most rhinitis patients (i) are not adherent and do not follow guidelines, (ii) use as-needed treatment, (iii) do not take medication when they are well, (iv) increase their treatment based on symptoms and (v) do not use the recommended treatment. The data also show that control (symptoms, work productivity, educational performance) is not always improved by medications. A combined symptom-medication score (ARIA-EAACI-CSMS) has been validated for clinical practice and trials. The implications of the novel MASK-air^® results should lead to change management in rhinitis and asthma.

Original language	English
Article number	e12215
Journal	Clinical and translational allergy
Volume	13
Issue number	1
DOIs	https://doi.org/10.1002/clt2.12215
Publication status	Published - 1 Jan 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

MASK-air
asthma
digital
mHealth
rhinitis

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Digitally-enabled-patient-centred-care-in-rhinitis-and-asthma-multimorbidity.pdfFinal published version, 2.83 MB

Cite this

Bousquet, J., Anto, J. M., Sousa-Pinto, B., Czarlewski, W., Bedbrook, A., Haahtela, T., Klimek, L., Pfaar, O., Kuna, P., Kupczyk, M., Regateiro, F. S., Samolinski, B., Valiulis, A., Yorgancioglu, A., Arnavielhe, S., Basaga?a, X., Bergmann, K. C., Bosnic-Anticevich, S., Brussino, L., ... Zuberbier, T. (2023). Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity: The ARIA-MASK-air? approach. Clinical and translational allergy, 13(1), Article e12215. https://doi.org/10.1002/clt2.12215

@article{45aaaa64379c406d9057e38943ed178f,

title = "Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity: The ARIA-MASK-air? approach",

abstract = "MASK-air{\textregistered}, a validated mHealth app (Medical Device regulation Class IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK-air{\textregistered} is a Good Practice of DG Sant{\'e} on digitally-enabled, patient-centred care. It is also a candidate Good Practice of OECD (Organisation for Economic Co-operation and Development). MASK-air{\textregistered} data has enabled novel phenotype discovery and characterisation, as well as novel insights into the management of allergic rhinitis. MASK-air{\textregistered} data show that most rhinitis patients (i) are not adherent and do not follow guidelines, (ii) use as-needed treatment, (iii) do not take medication when they are well, (iv) increase their treatment based on symptoms and (v) do not use the recommended treatment. The data also show that control (symptoms, work productivity, educational performance) is not always improved by medications. A combined symptom-medication score (ARIA-EAACI-CSMS) has been validated for clinical practice and trials. The implications of the novel MASK-air{\textregistered} results should lead to change management in rhinitis and asthma.",

keywords = "MASK-air, asthma, digital, mHealth, rhinitis",

author = "Jean Bousquet and Anto, \{Josep M.\} and Bernardo Sousa-Pinto and Wienczyslawa Czarlewski and Anna Bedbrook and Tari Haahtela and Ludger Klimek and Oliver Pfaar and Piotr Kuna and Maciej Kupczyk and Regateiro, \{Frederico S.\} and Boleslaw Samolinski and Arunas Valiulis and Arzu Yorgancioglu and Sylvie Arnavielhe and Xavier Basaga?a and Bergmann, \{Karl C.\} and Sinthia Bosnic-Anticevich and Luisa Brussino and Canonica, \{G. Walter\} and Victoria Cardona and Lorenzo Cecchi and Claudia Chaves-Loureiro and Elisio Costa and Cruz, \{Alvaro A.\} and Bilun Gemicioglu and Fokkens, \{Wytske J.\} and Ivancevich, \{Juan Carlos\} and Helga Kraxner and Violeta Kvedariene and Larenas-Linnemann, \{D. sir?e E.\} and Daniel Laune and Renaud Louis and Michael Makris and Marcus Maurer and Erik Mel?n and Yann Micheli and Mario Morais-Almeida and Joaquim Mullol and Marek Niedoszytko and Yoshitaka Okamoto and Papadopoulos, \{Nikolaos G.\} and Vincenzo Patella and Nh?n Pham-Thi and Rouadi, \{Philip W.\} and Joaquin Sastre and Nicola Scichilone and Aziz Sheikh and Mikhail Sofiev and Luis Taborda-Barata and Sanna Toppila-Salmi and Ioanna Tsiligianni and Erkka Valovirta and Ventura, \{Maria Teresa\} and Vieira, \{Rafael Jos?\} and Mihaela Zidarn and Rita Amaral and Ansotegui, \{Ignacio J.\} and Annabelle B?dard and Samuel Benveniste and Michael Bewick and Carsten Bindslev-Jensen and Hubert Blain and Matteo Bonini and Rodolphe Bourret and Fulvio Braido and Pedro Carreiro-Martins and Denis Charpin and Ivan Cherrez-Ojeda and Tomas Chivato and Chu, \{Derek K.\} and Cemal Cingi and \{del Giacco\}, Stefano and \{de Blay\}, Fr?d?ric and Philippe Devillier and \{de Vries\}, Govert and Maria Doulaptsi and Virginie Doyen and Dray, \{G. rard\} and Jean-Fran?ois Fontaine and Gomez, \{R. Maximiliano\} and Jan Hagemann and Enrico Heffler and Maja Hofmann and Ewa Jassem and Marek Jutel and Thomas Keil and Vicky Kritikos and Inger Kull and Marek Kulus and Olga Louren?o and Eve Mathieu-Dupas and Enrica Menditto and Ralph M?sges and Ruth Murray and Rachel Nadif and Hugo Neffen and Stefania Nicola and Robyn O?Hehir and Heidi Olze and Yuliia Palamarchuk and Jean-Louis P?pin and Benoit P?tr? and Robert Picard and Constantinos Pitsios and Francesca Puggioni and Santiago Quirce and Filip Raciborski and Sietze Reitsma and Nicolas Roche and Monica Rodriguez-Gonzalez and Jan Romantowski and Ana S?-Sousa and Serpa, \{Faradiba S.\} and Marine Savour? and Shamji, \{Mohamed H.\} and Milan Sova and Annette Sperl and Cristiana Stellato and Ana Todo-Bom and Tomazic, \{Peter Valentin\} and Olivier Vandenplas and \{van Eerd\}, Michiel and Tuula Vasankari and Fr?d?ric Viart and Susan Waserman and Fonseca, \{Joao A.\} and Torsten Zuberbier",

note = "Funding Information: The authors thank Ms V{\'e}ronique Pretschner for submitting the paper. MASK‐air has been supported by Charit{\'e} Universit{\"a}tsmedizin Berlin, EU grants (EU Structural and Development Funds Languedoc Roussillon and Region PACA; POLLAR: EIT Health; Twinning: EIP on AHA; Twinning DHE: H2020; Catalyse: Horizon Europe) and educational grants from Mylan‐Viatris, ALK, GSK, Novartis, Stallerg{\`e}nes‐Greer and Uriach. None for the study. {\textregistered} Publisher Copyright: {\textcopyright} 2023 The Authors. Clinical and Translational Allergy published by John Wiley \& Sons Ltd on behalf of European Academy of Allergy and Clinical Immunology.",

year = "2023",

month = jan,

day = "1",

doi = "10.1002/clt2.12215",

language = "English",

volume = "13",

journal = "Clinical and translational allergy",

issn = "2045-7022",

publisher = "John Wiley \& Sons Inc.",

number = "1",

}

Bousquet, J, Anto, JM, Sousa-Pinto, B, Czarlewski, W, Bedbrook, A, Haahtela, T, Klimek, L, Pfaar, O, Kuna, P, Kupczyk, M, Regateiro, FS, Samolinski, B, Valiulis, A, Yorgancioglu, A, Arnavielhe, S, Basaga?a, X, Bergmann, KC, Bosnic-Anticevich, S, Brussino, L, Canonica, GW, Cardona, V, Cecchi, L, Chaves-Loureiro, C, Costa, E, Cruz, AA, Gemicioglu, B, Fokkens, WJ, Ivancevich, JC, Kraxner, H, Kvedariene, V, Larenas-Linnemann, DSE, Laune, D, Louis, R, Makris, M, Maurer, M, Mel?n, E, Micheli, Y, Morais-Almeida, M, Mullol, J, Niedoszytko, M, Okamoto, Y, Papadopoulos, NG, Patella, V, Pham-Thi, N, Rouadi, PW, Sastre, J, Scichilone, N, Sheikh, A, Sofiev, M, Taborda-Barata, L, Toppila-Salmi, S, Tsiligianni, I, Valovirta, E, Ventura, MT, Vieira, RJ, Zidarn, M, Amaral, R, Ansotegui, IJ, B?dard, A, Benveniste, S, Bewick, M, Bindslev-Jensen, C, Blain, H, Bonini, M, Bourret, R, Braido, F, Carreiro-Martins, P, Charpin, D, Cherrez-Ojeda, I, Chivato, T, Chu, DK, Cingi, C, del Giacco, S, de Blay, F, Devillier, P, de Vries, G, Doulaptsi, M, Doyen, V, Dray, GR, Fontaine, J-F, Gomez, RM, Hagemann, J, Heffler, E, Hofmann, M, Jassem, E, Jutel, M, Keil, T, Kritikos, V, Kull, I, Kulus, M, Louren?o, O, Mathieu-Dupas, E, Menditto, E, M?sges, R, Murray, R, Nadif, R, Neffen, H, Nicola, S, O?Hehir, R, Olze, H, Palamarchuk, Y, P?pin, J-L, P?tr?, B, Picard, R, Pitsios, C, Puggioni, F, Quirce, S, Raciborski, F, Reitsma, S, Roche, N, Rodriguez-Gonzalez, M, Romantowski, J, S?-Sousa, A, Serpa, FS, Savour?, M, Shamji, MH, Sova, M, Sperl, A, Stellato, C, Todo-Bom, A, Tomazic, PV, Vandenplas, O, van Eerd, M, Vasankari, T, Viart, F, Waserman, S, Fonseca, JA & Zuberbier, T 2023, 'Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity: The ARIA-MASK-air? approach', Clinical and translational allergy, vol. 13, no. 1, e12215. https://doi.org/10.1002/clt2.12215

TY - JOUR

T1 - Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity

T2 - The ARIA-MASK-air? approach

AU - Bousquet, Jean

AU - Anto, Josep M.

AU - Sousa-Pinto, Bernardo

AU - Czarlewski, Wienczyslawa

AU - Bedbrook, Anna

AU - Haahtela, Tari

AU - Klimek, Ludger

AU - Pfaar, Oliver

AU - Kuna, Piotr

AU - Kupczyk, Maciej

AU - Regateiro, Frederico S.

AU - Samolinski, Boleslaw

AU - Valiulis, Arunas

AU - Yorgancioglu, Arzu

AU - Arnavielhe, Sylvie

AU - Basaga?a, Xavier

AU - Bergmann, Karl C.

AU - Bosnic-Anticevich, Sinthia

AU - Brussino, Luisa

AU - Canonica, G. Walter

AU - Cardona, Victoria

AU - Cecchi, Lorenzo

AU - Chaves-Loureiro, Claudia

AU - Costa, Elisio

AU - Cruz, Alvaro A.

AU - Gemicioglu, Bilun

AU - Fokkens, Wytske J.

AU - Ivancevich, Juan Carlos

AU - Kraxner, Helga

AU - Kvedariene, Violeta

AU - Larenas-Linnemann, D. sir?e E.

AU - Laune, Daniel

AU - Louis, Renaud

AU - Makris, Michael

AU - Maurer, Marcus

AU - Mel?n, Erik

AU - Micheli, Yann

AU - Morais-Almeida, Mario

AU - Mullol, Joaquim

AU - Niedoszytko, Marek

AU - Okamoto, Yoshitaka

AU - Papadopoulos, Nikolaos G.

AU - Patella, Vincenzo

AU - Pham-Thi, Nh?n

AU - Rouadi, Philip W.

AU - Sastre, Joaquin

AU - Scichilone, Nicola

AU - Sheikh, Aziz

AU - Sofiev, Mikhail

AU - Taborda-Barata, Luis

AU - Toppila-Salmi, Sanna

AU - Tsiligianni, Ioanna

AU - Valovirta, Erkka

AU - Ventura, Maria Teresa

AU - Vieira, Rafael Jos?

AU - Zidarn, Mihaela

AU - Amaral, Rita

AU - Ansotegui, Ignacio J.

AU - B?dard, Annabelle

AU - Benveniste, Samuel

AU - Bewick, Michael

AU - Bindslev-Jensen, Carsten

AU - Blain, Hubert

AU - Bonini, Matteo

AU - Bourret, Rodolphe

AU - Braido, Fulvio

AU - Carreiro-Martins, Pedro

AU - Charpin, Denis

AU - Cherrez-Ojeda, Ivan

AU - Chivato, Tomas

AU - Chu, Derek K.

AU - Cingi, Cemal

AU - del Giacco, Stefano

AU - de Blay, Fr?d?ric

AU - Devillier, Philippe

AU - de Vries, Govert

AU - Doulaptsi, Maria

AU - Doyen, Virginie

AU - Dray, G. rard

AU - Fontaine, Jean-Fran?ois

AU - Gomez, R. Maximiliano

AU - Hagemann, Jan

AU - Heffler, Enrico

AU - Hofmann, Maja

AU - Jassem, Ewa

AU - Jutel, Marek

AU - Keil, Thomas

AU - Kritikos, Vicky

AU - Kull, Inger

AU - Kulus, Marek

AU - Louren?o, Olga

AU - Mathieu-Dupas, Eve

AU - Menditto, Enrica

AU - M?sges, Ralph

AU - Murray, Ruth

AU - Nadif, Rachel

AU - Neffen, Hugo

AU - Nicola, Stefania

AU - O?Hehir, Robyn

AU - Olze, Heidi

AU - Palamarchuk, Yuliia

AU - P?pin, Jean-Louis

AU - P?tr?, Benoit

AU - Picard, Robert

AU - Pitsios, Constantinos

AU - Puggioni, Francesca

AU - Quirce, Santiago

AU - Raciborski, Filip

AU - Reitsma, Sietze

AU - Roche, Nicolas

AU - Rodriguez-Gonzalez, Monica

AU - Romantowski, Jan

AU - S?-Sousa, Ana

AU - Serpa, Faradiba S.

AU - Savour?, Marine

AU - Shamji, Mohamed H.

AU - Sova, Milan

AU - Sperl, Annette

AU - Stellato, Cristiana

AU - Todo-Bom, Ana

AU - Tomazic, Peter Valentin

AU - Vandenplas, Olivier

AU - van Eerd, Michiel

AU - Vasankari, Tuula

AU - Viart, Fr?d?ric

AU - Waserman, Susan

AU - Fonseca, Joao A.

AU - Zuberbier, Torsten

N1 - Funding Information: The authors thank Ms Véronique Pretschner for submitting the paper. MASK‐air has been supported by Charité Universitätsmedizin Berlin, EU grants (EU Structural and Development Funds Languedoc Roussillon and Region PACA; POLLAR: EIT Health; Twinning: EIP on AHA; Twinning DHE: H2020; Catalyse: Horizon Europe) and educational grants from Mylan‐Viatris, ALK, GSK, Novartis, Stallergènes‐Greer and Uriach. None for the study. ® Publisher Copyright: © 2023 The Authors. Clinical and Translational Allergy published by John Wiley & Sons Ltd on behalf of European Academy of Allergy and Clinical Immunology.

PY - 2023/1/1

Y1 - 2023/1/1

N2 - MASK-air®, a validated mHealth app (Medical Device regulation Class IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK-air® is a Good Practice of DG Santé on digitally-enabled, patient-centred care. It is also a candidate Good Practice of OECD (Organisation for Economic Co-operation and Development). MASK-air® data has enabled novel phenotype discovery and characterisation, as well as novel insights into the management of allergic rhinitis. MASK-air® data show that most rhinitis patients (i) are not adherent and do not follow guidelines, (ii) use as-needed treatment, (iii) do not take medication when they are well, (iv) increase their treatment based on symptoms and (v) do not use the recommended treatment. The data also show that control (symptoms, work productivity, educational performance) is not always improved by medications. A combined symptom-medication score (ARIA-EAACI-CSMS) has been validated for clinical practice and trials. The implications of the novel MASK-air® results should lead to change management in rhinitis and asthma.

AB - MASK-air®, a validated mHealth app (Medical Device regulation Class IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK-air® is a Good Practice of DG Santé on digitally-enabled, patient-centred care. It is also a candidate Good Practice of OECD (Organisation for Economic Co-operation and Development). MASK-air® data has enabled novel phenotype discovery and characterisation, as well as novel insights into the management of allergic rhinitis. MASK-air® data show that most rhinitis patients (i) are not adherent and do not follow guidelines, (ii) use as-needed treatment, (iii) do not take medication when they are well, (iv) increase their treatment based on symptoms and (v) do not use the recommended treatment. The data also show that control (symptoms, work productivity, educational performance) is not always improved by medications. A combined symptom-medication score (ARIA-EAACI-CSMS) has been validated for clinical practice and trials. The implications of the novel MASK-air® results should lead to change management in rhinitis and asthma.

KW - MASK-air

KW - asthma

KW - digital

KW - mHealth

KW - rhinitis

UR - https://www.scopus.com/pages/publications/85147105865

U2 - 10.1002/clt2.12215

DO - 10.1002/clt2.12215

M3 - Article

C2 - 36705508

SN - 2045-7022

VL - 13

JO - Clinical and translational allergy

JF - Clinical and translational allergy

IS - 1

M1 - e12215

ER -

Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity: The ARIA-MASK-air? approach

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