TY - JOUR
T1 - Determinants of quality of life in family caregivers in MCI
T2 - a comparison with mild dementia
AU - Tan, Eva Y. L.
AU - Janssen, Niels
AU - Handels, Ron
AU - Ramakers, Inez H. G. B.
AU - Verhey, Frans R. J.
AU - van der Flier, Wiesje M.
AU - Melis, René J. F.
AU - Olde Rikkert, Marcel G. M.
AU - Schols, Jos M. G. A.
AU - de Vugt, Marjolein E.
N1 - Funding Information:
The 4C study was performed within the framework of the Clinical Course of Cognition and Comorbidity in MCI (4C-MCI) Study and was funded by Alzheimer Nederland (grant number: 20083494). The Learn study was performed within the framework of CTMM, the Center for Translational Molecular Medicine (www.ctmm.nl), project LeARN (grant 02 N-101). The authors thank all persons, researchers and participants, who contributed to the 4C study and the Learn study. For the secondary data analyses in this study there was no specific funding.
Publisher Copyright:
© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
PY - 2023
Y1 - 2023
N2 - Objectives: The aim of the current study was to investigate the health-related quality of life (HRQol) of the family caregiver in MCI, explore possible determinants and study possible differences with mild dementia. Methods: This secondary data analysis included 145 persons with MCI and 154 persons with dementia and their family caregivers from two Dutch cohort studies. HRQoL was measured with the VAS of the EuroQol-5D-3L version. Regressions analyses were conducted to examine potential demographic and clinical determinants of the caregiver’s HRQoL. Results: The mean EQ5D-VAS in family caregivers of persons with MCI was 81.1 (SD 15.7), and did not significantly differ from family caregivers in mild dementia (81.9 (SD 13.0)). In MCI, patient measurements were not significantly associated with caregiver mean EQ5D-VAS. Concerning caregiver characteristics, being a spouse and a lower educational level were associated with a lower mean EQ5D-VAS (in a multiple linear regression model: unstandardized B −8.075, p = 0.013 and unstandardized B −6.162, p = 0.037 resp.). In mild dementia, the NPI item irritability showed an association with caregiver EQ5D-VAS in bivariate linear regression analyses. Conclusion: Results indicate that especially family caregiver characteristics seem to influence family caregiver HRQoL in MCI. Future research should include other potential determinants such as burden, coping strategies and relationship quality.
AB - Objectives: The aim of the current study was to investigate the health-related quality of life (HRQol) of the family caregiver in MCI, explore possible determinants and study possible differences with mild dementia. Methods: This secondary data analysis included 145 persons with MCI and 154 persons with dementia and their family caregivers from two Dutch cohort studies. HRQoL was measured with the VAS of the EuroQol-5D-3L version. Regressions analyses were conducted to examine potential demographic and clinical determinants of the caregiver’s HRQoL. Results: The mean EQ5D-VAS in family caregivers of persons with MCI was 81.1 (SD 15.7), and did not significantly differ from family caregivers in mild dementia (81.9 (SD 13.0)). In MCI, patient measurements were not significantly associated with caregiver mean EQ5D-VAS. Concerning caregiver characteristics, being a spouse and a lower educational level were associated with a lower mean EQ5D-VAS (in a multiple linear regression model: unstandardized B −8.075, p = 0.013 and unstandardized B −6.162, p = 0.037 resp.). In mild dementia, the NPI item irritability showed an association with caregiver EQ5D-VAS in bivariate linear regression analyses. Conclusion: Results indicate that especially family caregiver characteristics seem to influence family caregiver HRQoL in MCI. Future research should include other potential determinants such as burden, coping strategies and relationship quality.
KW - EQ5D-VAS
KW - Mild cognitive impairment
KW - dementia
KW - family caregiver
KW - quality of life
UR - https://www.scopus.com/pages/publications/85161892072
U2 - 10.1080/13607863.2023.2220274
DO - 10.1080/13607863.2023.2220274
M3 - Article
C2 - 37310855
SN - 1360-7863
VL - 27
SP - 1983
EP - 1989
JO - Aging and Mental Health
JF - Aging and Mental Health
IS - 10
ER -