Dendritic cell immunotherapy: mapping the way

Carl G. Figdor; I. Jolanda M. de Vries; W. Joost Lesterhuis; Cornelis J. M. Melief

doi:10.1038/nm1039

Dendritic cell immunotherapy: mapping the way

Carl G. Figdor
, I. Jolanda M. de Vries
, W. Joost Lesterhuis
, Cornelis J. M. Melief

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Dendritic cells (DCs) are the professional antigen-presenting cells of the immune system, with the potential to either stimulate or inhibit immune responses. Exploiting the immune-regulatory capacities of dendritic cells holds great promise for the treatment of cancer, autoimmune diseases and the prevention of transplant rejection. Although early clinical trials indicate that DC vaccines can induce immune responses in some cancer patients, careful study design and use of standardized clinical and immunological criteria are needed

Original language	English
Pages (from-to)	475-480
Journal	Nature medicine
Volume	10
Issue number	5
DOIs	https://doi.org/10.1038/nm1039
Publication status	Published - 2004

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title = "Dendritic cell immunotherapy: mapping the way",

abstract = "Dendritic cells (DCs) are the professional antigen-presenting cells of the immune system, with the potential to either stimulate or inhibit immune responses. Exploiting the immune-regulatory capacities of dendritic cells holds great promise for the treatment of cancer, autoimmune diseases and the prevention of transplant rejection. Although early clinical trials indicate that DC vaccines can induce immune responses in some cancer patients, careful study design and use of standardized clinical and immunological criteria are needed",

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AU - Lesterhuis, W. Joost

AU - Melief, Cornelis J. M.

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AB - Dendritic cells (DCs) are the professional antigen-presenting cells of the immune system, with the potential to either stimulate or inhibit immune responses. Exploiting the immune-regulatory capacities of dendritic cells holds great promise for the treatment of cancer, autoimmune diseases and the prevention of transplant rejection. Although early clinical trials indicate that DC vaccines can induce immune responses in some cancer patients, careful study design and use of standardized clinical and immunological criteria are needed

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JO - Nature medicine

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Dendritic cell immunotherapy: mapping the way

Abstract

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