Defining the Tumor Microenvironment of Penile Cancer by Means of the Cancer Immunogram

Hielke-Martijn de Vries; Sarah R. Ottenhof; Simon Horenblas; Michiel S. van der Heijden; Ekaterina S. Jordanova

doi:10.1016/j.euf.2019.02.019

Defining the Tumor Microenvironment of Penile Cancer by Means of the Cancer Immunogram

Hielke-Martijn de Vries
, Sarah R. Ottenhof
, Simon Horenblas
, Michiel S. van der Heijden
, Ekaterina S. Jordanova^*

^*Corresponding author for this work

Netherlands Cancer Institute
Amsterdam UMC - Vrije Universiteit Amsterdam
University of Amsterdam

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

CD8+ T-cell infiltration and PD-L1 expression are commonly observed in penile cancers, providing the rationale for immunotherapeutic treatment, particularly in advanced disease. Clinical trials testing checkpoint blockade are ongoing.

Original language	English
Pages (from-to)	718-721
Number of pages	4
Journal	European urology focus
Volume	5
Issue number	5
DOIs	https://doi.org/10.1016/j.euf.2019.02.019
Publication status	Published - 1 Sept 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Immunotherapy
Penile neoplasm
Tumor microenvironment

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10.1016/j.euf.2019.02.019

Cite this

@article{c125bc06a1914c52b68e03620fe04b81,

title = "Defining the Tumor Microenvironment of Penile Cancer by Means of the Cancer Immunogram",

abstract = "CD8+ T-cell infiltration and PD-L1 expression are commonly observed in penile cancers, providing the rationale for immunotherapeutic treatment, particularly in advanced disease. Clinical trials testing checkpoint blockade are ongoing.",

keywords = "Immunotherapy, Penile neoplasm, Tumor microenvironment",

author = "\{de Vries\}, Hielke-Martijn and Ottenhof, \{Sarah R.\} and Simon Horenblas and \{van der Heijden\}, \{Michiel S.\} and Jordanova, \{Ekaterina S.\}",

year = "2019",

month = sep,

day = "1",

doi = "10.1016/j.euf.2019.02.019",

language = "English",

volume = "5",

pages = "718--721",

journal = "European urology focus",

issn = "2405-4569",

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TY - JOUR

T1 - Defining the Tumor Microenvironment of Penile Cancer by Means of the Cancer Immunogram

AU - de Vries, Hielke-Martijn

AU - Ottenhof, Sarah R.

AU - Horenblas, Simon

AU - van der Heijden, Michiel S.

AU - Jordanova, Ekaterina S.

PY - 2019/9/1

Y1 - 2019/9/1

N2 - CD8+ T-cell infiltration and PD-L1 expression are commonly observed in penile cancers, providing the rationale for immunotherapeutic treatment, particularly in advanced disease. Clinical trials testing checkpoint blockade are ongoing.

AB - CD8+ T-cell infiltration and PD-L1 expression are commonly observed in penile cancers, providing the rationale for immunotherapeutic treatment, particularly in advanced disease. Clinical trials testing checkpoint blockade are ongoing.

KW - Immunotherapy

KW - Penile neoplasm

KW - Tumor microenvironment

UR - https://www.scopus.com/pages/publications/85062678910

UR - https://www.ncbi.nlm.nih.gov/pubmed/30862420

UR - https://www.scopus.com/pages/publications/85062678910

U2 - 10.1016/j.euf.2019.02.019

DO - 10.1016/j.euf.2019.02.019

M3 - Review article

C2 - 30862420

SN - 2405-4569

VL - 5

SP - 718

EP - 721

JO - European urology focus

JF - European urology focus

IS - 5

ER -

Defining the Tumor Microenvironment of Penile Cancer by Means of the Cancer Immunogram

Abstract

UN SDGs

Keywords

Access to Document

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