Deep brain stimulation for obsessive–compulsive disorder: a crisis of access

Veerle Visser-Vandewalle; Pablo Andrade; Philip E. Mosley; Benjamin D. Greenberg; Rick Schuurman; Nicole C. McLaughlin; Valerie Voon; Paul Krack; Kelly D. Foote; Helen S. Mayberg; Martijn Figee; Brian H. Kopell; Mircea Polosan; Eileen M. Joyce; Stephan Chabardes; Keith Matthews; Juan C. Baldermann; Himanshu Tyagi; Paul E. Holtzheimer; Chris Bervoets; Clement Hamani; Carine Karachi; Damiaan Denys; Ludvic Zrinzo; Patric Blomstedt; Matilda Naesström; Aviva Abosch; Steven Rasmussen; Volker A. Coenen; Thomas E. Schlaepfer; Darin D. Dougherty; Philippe Domenech; Peter Silburn; James Giordano; Andres M. Lozano; Sameer A. Sheth; Terry Coyne; Jens Kuhn; Luc Mallet; Bart Nuttin; Marwan Hariz; Michael S. Okun

doi:10.1038/s41591-022-01879-z

Deep brain stimulation for obsessive–compulsive disorder: a crisis of access

Veerle Visser-Vandewalle^*
, Pablo Andrade
, Philip E. Mosley
, Benjamin D. Greenberg
, Rick Schuurman
, Nicole C. McLaughlin
, Valerie Voon
, Paul Krack
, Kelly D. Foote
, Helen S. Mayberg
, Martijn Figee
, Brian H. Kopell
, Mircea Polosan
, Eileen M. Joyce
, Stephan Chabardes
, Keith Matthews
, Juan C. Baldermann
, Himanshu Tyagi
, Paul E. Holtzheimer
, Chris Bervoets

Clement Hamani, Carine Karachi, Damiaan Denys, Ludvic Zrinzo, Patric Blomstedt, Matilda Naesström, Aviva Abosch, Steven Rasmussen, Volker A. Coenen, Thomas E. Schlaepfer, Darin D. Dougherty, Philippe Domenech, Peter Silburn, James Giordano, Andres M. Lozano, Sameer A. Sheth, Terry Coyne, Jens Kuhn, Luc Mallet, Bart Nuttin, Marwan Hariz, Michael S. Okun

^*Corresponding author for this work

University of Cologne
University of Queensland
Brown University
VA RR&D Center for Neurorestoration and Neurotechnology
University of Cambridge
University of Bern
University of Florida
Icahn School of Medicine at Mount Sinai
Fondation FondaMental
Department of Anesthesiology & Intensive Care, University Hospital of Grenoble, Grenoble, France
Grenoble Institut des Neurosciences
University College London
School of Medicine Centre for Cardiovascular and Lung Biology, Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital & Medical School, Dundee, UK
Dartmouth College
KU Leuven
University of Toronto
Assistance publique – Hôpitaux de Paris
Umeå University
University of Colorado Anschutz Medical Campus
University of Freiburg
Harvard University
Hôpital Henri Mondor
Sorbonne Université
Georgetown University
Division of Neuroradiology, Joint Department of Medical Imaging and Neurosurgery, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
Baylor College of Medicine
Johanniter Hospital Oberhausen
University of Geneva

Research output: Contribution to journal › Comment/Letter to the editor › Academic

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Original language	English
Pages (from-to)	1529-1532
Number of pages	4
Journal	Nature medicine
Volume	28
Issue number	8
Early online date	2022
DOIs	https://doi.org/10.1038/s41591-022-01879-z
Publication status	Published - Aug 2022

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Deep-brain-stimulation-for-obsessivecompulsive-disorder.pdfFinal published version, 970 KBLicence: Taverne

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Visser-Vandewalle, V., Andrade, P., Mosley, P. E., Greenberg, B. D., Schuurman, R., McLaughlin, N. C., Voon, V., Krack, P., Foote, K. D., Mayberg, H. S., Figee, M., Kopell, B. H., Polosan, M., Joyce, E. M., Chabardes, S., Matthews, K., Baldermann, J. C., Tyagi, H., Holtzheimer, P. E., ... Okun, M. S. (2022). Deep brain stimulation for obsessive–compulsive disorder: a crisis of access. Nature medicine, 28(8), 1529-1532. https://doi.org/10.1038/s41591-022-01879-z

@article{c0eb8675acc94b6ab6cba72ba07948be,

title = "Deep brain stimulation for obsessive–compulsive disorder: a crisis of access",

author = "Veerle Visser-Vandewalle and Pablo Andrade and Mosley, \{Philip E.\} and Greenberg, \{Benjamin D.\} and Rick Schuurman and McLaughlin, \{Nicole C.\} and Valerie Voon and Paul Krack and Foote, \{Kelly D.\} and Mayberg, \{Helen S.\} and Martijn Figee and Kopell, \{Brian H.\} and Mircea Polosan and Joyce, \{Eileen M.\} and Stephan Chabardes and Keith Matthews and Baldermann, \{Juan C.\} and Himanshu Tyagi and Holtzheimer, \{Paul E.\} and Chris Bervoets and Clement Hamani and Carine Karachi and Damiaan Denys and Ludvic Zrinzo and Patric Blomstedt and Matilda Naesstr{\"o}m and Aviva Abosch and Steven Rasmussen and Coenen, \{Volker A.\} and Schlaepfer, \{Thomas E.\} and Dougherty, \{Darin D.\} and Philippe Domenech and Peter Silburn and James Giordano and Lozano, \{Andres M.\} and Sheth, \{Sameer A.\} and Terry Coyne and Jens Kuhn and Luc Mallet and Bart Nuttin and Marwan Hariz and Okun, \{Michael S.\}",

note = "Funding Information: P.K. reports research or educational grants from the Swiss National Science Foundation (FNS 323530\_177577, FNS 2020 32003BL\_197709-1 and FNS 33IC30\_198772), paid to his employing institution. M.S.O. has received research grants from the US National Institutes of Health (R01 NR014852, R01NS096008, UH3NS119844 and U01NS119562; training grant R25NS108939 (Principal Investigator)). Funding Information: V.V.-V. is a member of advisory boards and has received speaker{\textquoteright}s honoraria from Medtronic, Boston Scientific and Abbott. P.K. reports research or educational grants from Roger de Spoelberch Foundation, Bertarelli Foundation, Annemarie Opprecht Foundation, Parkinson Schweiz, Michael J. Fox Foundation, Aleva Neurotherapeutics, Boston Scientific, Medtronic, GE Healthcare and Idorsia, paid to his employing institution; lecturing fees from Boston Scientific and Bial, paid to his employing institution; travel expenses to scientific meetings from Boston Scientific, Zambon and Abbvie. L.Z. has received honoraria for educational activities from Elekta, Boston Scientific and Medtronic. A.M.L. has consulted for Medtronic, Boston Scientific and Abbott. S.A.S. has consulted for Boston Scientific, Neuropace and Zimmer Biomet. M.S.O. serves as medical advisor for the Parkinson{\textquoteright}s Foundation; has received research grants from Parkinson{\textquoteright}s Foundation, the Michael J. Fox Foundation, the Parkinson Alliance, Smallwood Foundation, the Bachmann-Strauss Foundation, the Tourette Syndrome Association, and the UF Foundation; and has received royalties for publications with Demos, Manson, Amazon, Smashwords, Books4Patients, Perseus, Robert Rose, Oxford and Cambridge. All other authors declare no competing interests.",

year = "2022",

month = aug,

doi = "10.1038/s41591-022-01879-z",

language = "English",

volume = "28",

pages = "1529--1532",

journal = "Nature medicine",

issn = "1078-8956",

publisher = "Nature Publishing Group",

number = "8",

}

Visser-Vandewalle, V, Andrade, P, Mosley, PE, Greenberg, BD, Schuurman, R, McLaughlin, NC, Voon, V, Krack, P, Foote, KD, Mayberg, HS, Figee, M, Kopell, BH, Polosan, M, Joyce, EM, Chabardes, S, Matthews, K, Baldermann, JC, Tyagi, H, Holtzheimer, PE, Bervoets, C, Hamani, C, Karachi, C, Denys, D, Zrinzo, L, Blomstedt, P, Naesström, M, Abosch, A, Rasmussen, S, Coenen, VA, Schlaepfer, TE, Dougherty, DD, Domenech, P, Silburn, P, Giordano, J, Lozano, AM, Sheth, SA, Coyne, T, Kuhn, J, Mallet, L, Nuttin, B, Hariz, M & Okun, MS 2022, 'Deep brain stimulation for obsessive–compulsive disorder: a crisis of access', Nature medicine, vol. 28, no. 8, pp. 1529-1532. https://doi.org/10.1038/s41591-022-01879-z

TY - JOUR

T1 - Deep brain stimulation for obsessive–compulsive disorder

T2 - a crisis of access

AU - Visser-Vandewalle, Veerle

AU - Andrade, Pablo

AU - Mosley, Philip E.

AU - Greenberg, Benjamin D.

AU - Schuurman, Rick

AU - McLaughlin, Nicole C.

AU - Voon, Valerie

AU - Krack, Paul

AU - Foote, Kelly D.

AU - Mayberg, Helen S.

AU - Figee, Martijn

AU - Kopell, Brian H.

AU - Polosan, Mircea

AU - Joyce, Eileen M.

AU - Chabardes, Stephan

AU - Matthews, Keith

AU - Baldermann, Juan C.

AU - Tyagi, Himanshu

AU - Holtzheimer, Paul E.

AU - Bervoets, Chris

AU - Hamani, Clement

AU - Karachi, Carine

AU - Denys, Damiaan

AU - Zrinzo, Ludvic

AU - Blomstedt, Patric

AU - Naesström, Matilda

AU - Abosch, Aviva

AU - Rasmussen, Steven

AU - Coenen, Volker A.

AU - Schlaepfer, Thomas E.

AU - Dougherty, Darin D.

AU - Domenech, Philippe

AU - Silburn, Peter

AU - Giordano, James

AU - Lozano, Andres M.

AU - Sheth, Sameer A.

AU - Coyne, Terry

AU - Kuhn, Jens

AU - Mallet, Luc

AU - Nuttin, Bart

AU - Hariz, Marwan

AU - Okun, Michael S.

N1 - Funding Information: P.K. reports research or educational grants from the Swiss National Science Foundation (FNS 323530_177577, FNS 2020 32003BL_197709-1 and FNS 33IC30_198772), paid to his employing institution. M.S.O. has received research grants from the US National Institutes of Health (R01 NR014852, R01NS096008, UH3NS119844 and U01NS119562; training grant R25NS108939 (Principal Investigator)). Funding Information: V.V.-V. is a member of advisory boards and has received speaker’s honoraria from Medtronic, Boston Scientific and Abbott. P.K. reports research or educational grants from Roger de Spoelberch Foundation, Bertarelli Foundation, Annemarie Opprecht Foundation, Parkinson Schweiz, Michael J. Fox Foundation, Aleva Neurotherapeutics, Boston Scientific, Medtronic, GE Healthcare and Idorsia, paid to his employing institution; lecturing fees from Boston Scientific and Bial, paid to his employing institution; travel expenses to scientific meetings from Boston Scientific, Zambon and Abbvie. L.Z. has received honoraria for educational activities from Elekta, Boston Scientific and Medtronic. A.M.L. has consulted for Medtronic, Boston Scientific and Abbott. S.A.S. has consulted for Boston Scientific, Neuropace and Zimmer Biomet. M.S.O. serves as medical advisor for the Parkinson’s Foundation; has received research grants from Parkinson’s Foundation, the Michael J. Fox Foundation, the Parkinson Alliance, Smallwood Foundation, the Bachmann-Strauss Foundation, the Tourette Syndrome Association, and the UF Foundation; and has received royalties for publications with Demos, Manson, Amazon, Smashwords, Books4Patients, Perseus, Robert Rose, Oxford and Cambridge. All other authors declare no competing interests.

PY - 2022/8

Y1 - 2022/8

UR - https://www.scopus.com/pages/publications/85133949797

U2 - 10.1038/s41591-022-01879-z

DO - 10.1038/s41591-022-01879-z

M3 - Comment/Letter to the editor

C2 - 35840727

SN - 1078-8956

VL - 28

SP - 1529

EP - 1532

JO - Nature medicine

JF - Nature medicine

IS - 8

ER -

Deep brain stimulation for obsessive–compulsive disorder: a crisis of access

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