Cytopathic effects of non-syncytium-inducing and syncytium-inducing human immunodeficiency virus type 1 variants on different CD4(+)-T-cell subsets are determined only by coreceptor expression

D. Kwa; J. Vingerhoed; B. Boeser-Nunnink; S. Broersen; H. Schuitemaker

doi:10.1128/JVI.75.21.10455-10459.2001

Cytopathic effects of non-syncytium-inducing and syncytium-inducing human immunodeficiency virus type 1 variants on different CD4(+)-T-cell subsets are determined only by coreceptor expression

D. Kwa
, J. Vingerhoed
, B. Boeser-Nunnink
, S. Broersen
, H. Schuitemaker

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In peripheral blood mononuclear cells, syncytium-inducing (SI) human immunodeficiency virus type 1 (HIV-1) infected and depleted all CD4(+) T cells, including naive T cells. Non-SI HIV-1 infected and depleted only the CCR5-expressing T-cell subset. This may explain the accelerated CD4 cell loss after SI conversion in vivo

Original language	English
Pages (from-to)	10455-10459
Journal	Journal of virology
Volume	75
Issue number	21
DOIs	https://doi.org/10.1128/JVI.75.21.10455-10459.2001
Publication status	Published - 2001

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1128/JVI.75.21.10455-10459.2001

Cite this

Kwa, D., Vingerhoed, J., Boeser-Nunnink, B., Broersen, S., & Schuitemaker, H. (2001). Cytopathic effects of non-syncytium-inducing and syncytium-inducing human immunodeficiency virus type 1 variants on different CD4(+)-T-cell subsets are determined only by coreceptor expression. Journal of virology, 75(21), 10455-10459. https://doi.org/10.1128/JVI.75.21.10455-10459.2001

@article{75525ff568644960a2dd04c343e3730d,

title = "Cytopathic effects of non-syncytium-inducing and syncytium-inducing human immunodeficiency virus type 1 variants on different CD4(+)-T-cell subsets are determined only by coreceptor expression",

abstract = "In peripheral blood mononuclear cells, syncytium-inducing (SI) human immunodeficiency virus type 1 (HIV-1) infected and depleted all CD4(+) T cells, including naive T cells. Non-SI HIV-1 infected and depleted only the CCR5-expressing T-cell subset. This may explain the accelerated CD4 cell loss after SI conversion in vivo",

author = "D. Kwa and J. Vingerhoed and B. Boeser-Nunnink and S. Broersen and H. Schuitemaker",

year = "2001",

doi = "10.1128/JVI.75.21.10455-10459.2001",

language = "English",

volume = "75",

pages = "10455--10459",

journal = "Journal of virology",

issn = "0022-538X",

publisher = "American Society for Microbiology",

number = "21",

}

Kwa, D, Vingerhoed, J, Boeser-Nunnink, B, Broersen, S & Schuitemaker, H 2001, 'Cytopathic effects of non-syncytium-inducing and syncytium-inducing human immunodeficiency virus type 1 variants on different CD4(+)-T-cell subsets are determined only by coreceptor expression', Journal of virology, vol. 75, no. 21, pp. 10455-10459. https://doi.org/10.1128/JVI.75.21.10455-10459.2001

Cytopathic effects of non-syncytium-inducing and syncytium-inducing human immunodeficiency virus type 1 variants on different CD4(+)-T-cell subsets are determined only by coreceptor expression. / Kwa, D.; Vingerhoed, J.; Boeser-Nunnink, B. et al.
In: Journal of virology, Vol. 75, No. 21, 2001, p. 10455-10459.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Cytopathic effects of non-syncytium-inducing and syncytium-inducing human immunodeficiency virus type 1 variants on different CD4(+)-T-cell subsets are determined only by coreceptor expression

AU - Kwa, D.

AU - Vingerhoed, J.

AU - Boeser-Nunnink, B.

AU - Broersen, S.

AU - Schuitemaker, H.

PY - 2001

Y1 - 2001

N2 - In peripheral blood mononuclear cells, syncytium-inducing (SI) human immunodeficiency virus type 1 (HIV-1) infected and depleted all CD4(+) T cells, including naive T cells. Non-SI HIV-1 infected and depleted only the CCR5-expressing T-cell subset. This may explain the accelerated CD4 cell loss after SI conversion in vivo

AB - In peripheral blood mononuclear cells, syncytium-inducing (SI) human immunodeficiency virus type 1 (HIV-1) infected and depleted all CD4(+) T cells, including naive T cells. Non-SI HIV-1 infected and depleted only the CCR5-expressing T-cell subset. This may explain the accelerated CD4 cell loss after SI conversion in vivo

U2 - 10.1128/JVI.75.21.10455-10459.2001

DO - 10.1128/JVI.75.21.10455-10459.2001

M3 - Article

C2 - 11581413

SN - 0022-538X

VL - 75

SP - 10455

EP - 10459

JO - Journal of virology

JF - Journal of virology

IS - 21

ER -

Cytopathic effects of non-syncytium-inducing and syncytium-inducing human immunodeficiency virus type 1 variants on different CD4(+)-T-cell subsets are determined only by coreceptor expression

Abstract

UN SDGs

Access to Document

Fingerprint

Cite this