Curcumin use by patients and healthy individuals: A critical examination of different formulations and their pharmacokinetics

M.A.G.M. Kroon

Curcumin use by patients and healthy individuals: A critical examination of different formulations and their pharmacokinetics

M.A.G.M. Kroon

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

Abstract

This thesis critically examines curcumin’s pharmacokinetics and bioavailability across various formulations in both patients and healthy individuals. A validated HPLC-MS/MS method (Chapter 2) was developed to quantify curcumin and its metabolites in human plasma, urine, and feces, distinguishing unconjugated from total (unconjugated + conjugated) curcumin. An

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Amsterdam
Supervisors/Advisors	van Laarhoven, Hanneke, Supervisor Swart, Eleonora L., Supervisor Kemper, Marleen, Co-supervisor van Tellingen, O., Co-supervisor, External person
Award date	15 Apr 2025
Publication status	Published - 2025

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AB - This thesis critically examines curcumin’s pharmacokinetics and bioavailability across various formulations in both patients and healthy individuals. A validated HPLC-MS/MS method (Chapter 2) was developed to quantify curcumin and its metabolites in human plasma, urine, and feces, distinguishing unconjugated from total (unconjugated + conjugated) curcumin. An

M3 - Phd-Thesis - Research and graduation internal

ER -

Curcumin use by patients and healthy individuals: A critical examination of different formulations and their pharmacokinetics

Abstract

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