TY - JOUR
T1 - Criteria voor geneesmiddelkeuze
T2 - Kwetsbare ouderen en antidepressiva
AU - Van Ojik, Annette L.
AU - Huisman-Baron, Marieke
AU - Van Der Veen, Lucia
AU - Jansen, Paul A.F.
AU - Brouwers, Jacobus R.B.J.
AU - Van Marum, Rob J.
AU - Van Roon, Eric N.
PY - 2012/7/1
Y1 - 2012/7/1
N2 - Pharmacotherapy in frail elderly is complicated and driven by multiple issues. As a result, physicians are faced with a complex task when prescribing to frail elderly patients. In this study, initiated by the Expertise Centre Pharmacotherapy for Older Persons (Ephor), a validated set of 23 criteria concerning effectiveness, safety, experience and convenience was developed to assist in the selection of the most appropriate drug within a drug class for the treatment of frail elderly patients. This method, using the 23 criteria, provides a complete overview of the relevant evidence for each individual drug. Evidence-based recommendations can be formulated for each individual drug within a drug class based on the pros and cons for frail elderly patients. Meanwhile, Ephor has formulated evidence-based recommendations for the antipsychotics, NSAIDs, ACE-inhibitors, opioids, hypnotics, anxiolytics, tricyclic antidepressants and second generation antidepressants. The complete reports are available at www.ephor.eu. As an example, a summary of the reports of the tricyclic antidepressants and second generation antidepressants is given.
AB - Pharmacotherapy in frail elderly is complicated and driven by multiple issues. As a result, physicians are faced with a complex task when prescribing to frail elderly patients. In this study, initiated by the Expertise Centre Pharmacotherapy for Older Persons (Ephor), a validated set of 23 criteria concerning effectiveness, safety, experience and convenience was developed to assist in the selection of the most appropriate drug within a drug class for the treatment of frail elderly patients. This method, using the 23 criteria, provides a complete overview of the relevant evidence for each individual drug. Evidence-based recommendations can be formulated for each individual drug within a drug class based on the pros and cons for frail elderly patients. Meanwhile, Ephor has formulated evidence-based recommendations for the antipsychotics, NSAIDs, ACE-inhibitors, opioids, hypnotics, anxiolytics, tricyclic antidepressants and second generation antidepressants. The complete reports are available at www.ephor.eu. As an example, a summary of the reports of the tricyclic antidepressants and second generation antidepressants is given.
UR - http://www.scopus.com/inward/record.url?scp=84875428135&partnerID=8YFLogxK
M3 - Article
SN - 1879-4637
VL - 37
SP - 141
EP - 147
JO - Tijdschrift voor Ouderengeneeskunde
JF - Tijdschrift voor Ouderengeneeskunde
IS - 3
ER -