Cover picture: eur. J. Immunol. 9/11

This month's cover depicts, by virtue of the scales, the balance of experts' opinions that are provided in the featured Macrophage Viewpoint series. Superimposed on the scales are cartoon drawings of the different macrophage subtypes (classical, alternative and regulatory) discussed by Fleming and Mosser (pp. 2498-2502); the background is kindly provided by Joan Stein-Streilein and is reprinted with permission from Faunce, D. E. et al., J. Immunol. 2001. 166: 313-321 (© 2001 The American Association of Immunologists, Inc.). The background shows migrating F4/80(+) APCs (pink) forming clusters with NKT and B cells in the marginal zone of mouse spleen, in the ACAID model of peripheral tolerance. The F4/80 antigen is discussed in the Viewpoint by Siamon Gordon et al. (pp. 2472-2476), and the paper first describing the F4/80 antibody features as one of the EJI classics on the EJI homepage (www.eji-journal.eu)