Correcting the drug development paradigm for glioblastoma requires serial tissue sampling

Kirit Singh; Kelly M. Hotchkiss; Ian F. Parney; John de Groot; Solmaz Sahebjam; Nader Sanai; Michael Platten; Evanthia Galanis; Michael Lim; Patrick Y. Wen; Giuseppe Minniti; Howard Colman; Timothy F. Cloughesy; Minesh P. Mehta; Marjolein Geurts; Isabel Arrillaga-Romany; Annick Desjardins; Kirk Tanner; Susan Short; David Arons; Elizabeth Duke; Wolfgang Wick; Stephen J. Bagley; David M. Ashley; Priya Kumthekar; Roel Verhaak; Anthony J. Chalmers; Anoop P. Patel; Colin Watts; Peter E. Fecci; Tracy T. Batchelor; Michael Weller; Michael A. Vogelbaum; Matthias Preusser; Mitchel S. Berger; Mustafa Khasraw

doi:10.1038/s41591-023-02464-8

Correcting the drug development paradigm for glioblastoma requires serial tissue sampling

Kirit Singh
, Kelly M. Hotchkiss
, Ian F. Parney
, John de Groot
, Solmaz Sahebjam
, Nader Sanai
, Michael Platten
, Evanthia Galanis
, Michael Lim
, Patrick Y. Wen
, Giuseppe Minniti
, Howard Colman
, Timothy F. Cloughesy
, Minesh P. Mehta
, Marjolein Geurts
, Isabel Arrillaga-Romany
, Annick Desjardins
, Kirk Tanner
, Susan Short
, David Arons

Elizabeth Duke, Wolfgang Wick, Stephen J. Bagley, David M. Ashley, Priya Kumthekar, Roel Verhaak, Anthony J. Chalmers, Anoop P. Patel, Colin Watts, Peter E. Fecci, Tracy T. Batchelor, Michael Weller, Michael A. Vogelbaum, Matthias Preusser, Mitchel S. Berger, Mustafa Khasraw^*

^*Corresponding author for this work

Duke University
Mayo Clinic Rochester, MN
University of California at San Francisco
National Institutes of Health
St. Joseph's Hospital and Medical Center, Phoenix
Heidelberg University
National Center for Tumor Diseases Heidelberg
Stanford University
Dana-Farber Cancer Institute
University of Rome La Sapienza
Huntsman Cancer Center Salt Lake City
University of California at Los Angeles
Miami Cancer Institute
Erasmus University Rotterdam
Brigham and Women’s Hospital
National Brain Tumor Society, Newton, Massachusetts, USA
University of Leeds
United States Food and Drug Administration
Ruprecht-Karls-University
University of Pennsylvania
Northwestern University Feinberg School of Medicine
Yale University School of Medicine
University of Glasgow
University of Birmingham
Duke University Medical Center
University Hospital Zürich
H. Lee Moffitt Cancer Center and Research Institute
Medical University of Vienna

Research output: Contribution to journal › Comment/Letter to the editor › Academic

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Original language	English
Pages (from-to)	2402-2405
Number of pages	4
Journal	Nature medicine
Volume	29
Issue number	10
Early online date	2023
DOIs	https://doi.org/10.1038/s41591-023-02464-8
Publication status	Published - Oct 2023

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SDG 3 Good Health and Well-being

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10.1038/s41591-023-02464-8

Correcting-the-drug-development-paradigm-for-glioblastoma-requires-serial-tissue-sampling.pdfFinal published version, 1.13 MBLicence: Taverne

Cite this

Singh, K., Hotchkiss, K. M., Parney, I. F., de Groot, J., Sahebjam, S., Sanai, N., Platten, M., Galanis, E., Lim, M., Wen, P. Y., Minniti, G., Colman, H., Cloughesy, T. F., Mehta, M. P., Geurts, M., Arrillaga-Romany, I., Desjardins, A., Tanner, K., Short, S., ... Khasraw, M. (2023). Correcting the drug development paradigm for glioblastoma requires serial tissue sampling. Nature medicine, 29(10), 2402-2405. https://doi.org/10.1038/s41591-023-02464-8

@article{78b918e644a146989f1fea6f046ece74,

title = "Correcting the drug development paradigm for glioblastoma requires serial tissue sampling",

author = "Kirit Singh and Hotchkiss, \{Kelly M.\} and Parney, \{Ian F.\} and \{de Groot\}, John and Solmaz Sahebjam and Nader Sanai and Michael Platten and Evanthia Galanis and Michael Lim and Wen, \{Patrick Y.\} and Giuseppe Minniti and Howard Colman and Cloughesy, \{Timothy F.\} and Mehta, \{Minesh P.\} and Marjolein Geurts and Isabel Arrillaga-Romany and Annick Desjardins and Kirk Tanner and Susan Short and David Arons and Elizabeth Duke and Wolfgang Wick and Bagley, \{Stephen J.\} and Ashley, \{David M.\} and Priya Kumthekar and Roel Verhaak and Chalmers, \{Anthony J.\} and Patel, \{Anoop P.\} and Colin Watts and Fecci, \{Peter E.\} and Batchelor, \{Tracy T.\} and Michael Weller and Vogelbaum, \{Michael A.\} and Matthias Preusser and Berger, \{Mitchel S.\} and Mustafa Khasraw",

note = "Funding Information: We thank C. Haynes, M. Bell-Johnston, S. Pressley and the other SNO staff for their administrative and logistical support; and M. Espey, S. Forry, L. Hubbard and A. Tawab-Amiri for their input and review of the manuscript. This article represents the opinion of the authors. It does not represent the opinion or policy of the National Institutes of Health of the US Federal Government.",

year = "2023",

month = oct,

doi = "10.1038/s41591-023-02464-8",

language = "English",

volume = "29",

pages = "2402--2405",

journal = "Nature medicine",

issn = "1078-8956",

publisher = "Nature Publishing Group",

number = "10",

}

Singh, K, Hotchkiss, KM, Parney, IF, de Groot, J, Sahebjam, S, Sanai, N, Platten, M, Galanis, E, Lim, M, Wen, PY, Minniti, G, Colman, H, Cloughesy, TF, Mehta, MP, Geurts, M, Arrillaga-Romany, I, Desjardins, A, Tanner, K, Short, S, Arons, D, Duke, E, Wick, W, Bagley, SJ, Ashley, DM, Kumthekar, P, Verhaak, R, Chalmers, AJ, Patel, AP, Watts, C, Fecci, PE, Batchelor, TT, Weller, M, Vogelbaum, MA, Preusser, M, Berger, MS & Khasraw, M 2023, 'Correcting the drug development paradigm for glioblastoma requires serial tissue sampling', Nature medicine, vol. 29, no. 10, pp. 2402-2405. https://doi.org/10.1038/s41591-023-02464-8

TY - JOUR

T1 - Correcting the drug development paradigm for glioblastoma requires serial tissue sampling

AU - Singh, Kirit

AU - Hotchkiss, Kelly M.

AU - Parney, Ian F.

AU - de Groot, John

AU - Sahebjam, Solmaz

AU - Sanai, Nader

AU - Platten, Michael

AU - Galanis, Evanthia

AU - Lim, Michael

AU - Wen, Patrick Y.

AU - Minniti, Giuseppe

AU - Colman, Howard

AU - Cloughesy, Timothy F.

AU - Mehta, Minesh P.

AU - Geurts, Marjolein

AU - Arrillaga-Romany, Isabel

AU - Desjardins, Annick

AU - Tanner, Kirk

AU - Short, Susan

AU - Arons, David

AU - Duke, Elizabeth

AU - Wick, Wolfgang

AU - Bagley, Stephen J.

AU - Ashley, David M.

AU - Kumthekar, Priya

AU - Verhaak, Roel

AU - Chalmers, Anthony J.

AU - Patel, Anoop P.

AU - Watts, Colin

AU - Fecci, Peter E.

AU - Batchelor, Tracy T.

AU - Weller, Michael

AU - Vogelbaum, Michael A.

AU - Preusser, Matthias

AU - Berger, Mitchel S.

AU - Khasraw, Mustafa

N1 - Funding Information: We thank C. Haynes, M. Bell-Johnston, S. Pressley and the other SNO staff for their administrative and logistical support; and M. Espey, S. Forry, L. Hubbard and A. Tawab-Amiri for their input and review of the manuscript. This article represents the opinion of the authors. It does not represent the opinion or policy of the National Institutes of Health of the US Federal Government.

PY - 2023/10

Y1 - 2023/10

UR - https://www.scopus.com/pages/publications/85165492210

U2 - 10.1038/s41591-023-02464-8

DO - 10.1038/s41591-023-02464-8

M3 - Comment/Letter to the editor

C2 - 37488293

SN - 1078-8956

VL - 29

SP - 2402

EP - 2405

JO - Nature medicine

JF - Nature medicine

IS - 10

ER -

Correcting the drug development paradigm for glioblastoma requires serial tissue sampling

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