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Concurrent upregulation of urokinase plasminogen activator receptor and CD11b during tuberculosis and experimental endotoxemia

  • N. P. Juffermans
  • , P. E. Dekkers
  • , A. Verbon
  • , P. Speelman
  • , S. J. van Deventer
  • , T. van der Poll

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Patients with tuberculosis had higher expression of monocyte urokinase receptor (uPAR) and CD11b than controls. In vitro, lipoarabinomannan and lipopolysaccharide (LPS) from Escherichia coli shared the ability to enhance uPAR and CD11b expression on monocytes and granulocytes. In healthy volunteers, LPS induced increases in monocyte and granulocyte uPAR and CD11b
Original languageEnglish
Pages (from-to)5182-5185
JournalInfection and immunity
Volume69
Issue number8
DOIs
Publication statusPublished - 2001

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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