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Comparison of sic 'Third-Generation' tests for the detection of HBsAg

  • H. W. Reesink
  • , L. J. Lafeber-Schut
  • , C. Aaij
  • , E. E. Reerink-Brongers

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Six 'third-generation' techniques for the detection of HBsAg were compared, i.e. Ausria II-125, Travenol-RIA, Auszyme, Hepanostika, Auscell and a modified Auscell technique applying centrifugation instead of sedimentation. The Ausria II-125 was the most sensitive test, followed by Travenol-RIA, both Auscell techniques, Auszyme and Hepanostika. In the Ausria II-125, Hepanostika and Auscell techniques, 1-2% of false-positive results were found in serum and 2% in plasma specimens from blood donors. Both the Travenol-RIA and Auszyme tests gave an unacceptably high percentage (6-8%) of false-positive results in both serum and plasma specimens
Original languageEnglish
Pages (from-to)61-72
JournalVox sanguinis
Volume39
Issue number2
DOIs
Publication statusPublished - 1980

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