Comparison of serological assays for detection of Chlamydia trachomatis antibodies in different groups of obstetrical and gynecological patients

C. J. Bax; J. A.E.M. Mutsaers; C. L. Jansen; J. B. Trimbos; P. J. Dörr; P. M. Oostvogel

doi:10.1128/CDLI.10.1.174-176.2003

Comparison of serological assays for detection of Chlamydia trachomatis antibodies in different groups of obstetrical and gynecological patients

C. J. Bax^*
, J. A.E.M. Mutsaers
, C. L. Jansen
, J. B. Trimbos
, P. J. Dörr
, P. M. Oostvogel

^*Corresponding author for this work

Haaglanden Medisch Centrum
Leiden University

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

New serological enzyme immunoassays (EIAs) were compared with microimmunofluorescence (MIF) as a "gold standard" to detect Chlamydia trachomatis antibodies in different groups of obstetrical, gynecological, and subfertile patients. There were no significant differences in seroprevalence rates, except for the group of C. trachomatis-positive patients (P < 0.01). Test characteristics were calculated for Chlamydia-EIA (Biologische Analysensystem GmbH, Lich, Germany) and pELISA (Medac, Wedel, Germany). pELISA seems to be a good alternative to MIF. It has high specificity and is easier to perform.

Original language	English
Pages (from-to)	174-176
Number of pages	3
Journal	Clinical and diagnostic laboratory immunology
Volume	10
Issue number	1
DOIs	https://doi.org/10.1128/CDLI.10.1.174-176.2003
Publication status	Published - Jan 2003

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10.1128/CDLI.10.1.174-176.2003

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title = "Comparison of serological assays for detection of Chlamydia trachomatis antibodies in different groups of obstetrical and gynecological patients",

abstract = "New serological enzyme immunoassays (EIAs) were compared with microimmunofluorescence (MIF) as a {"}gold standard{"} to detect Chlamydia trachomatis antibodies in different groups of obstetrical, gynecological, and subfertile patients. There were no significant differences in seroprevalence rates, except for the group of C. trachomatis-positive patients (P < 0.01). Test characteristics were calculated for Chlamydia-EIA (Biologische Analysensystem GmbH, Lich, Germany) and pELISA (Medac, Wedel, Germany). pELISA seems to be a good alternative to MIF. It has high specificity and is easier to perform.",

author = "Bax, \{C. J.\} and Mutsaers, \{J. A.E.M.\} and Jansen, \{C. L.\} and Trimbos, \{J. B.\} and D{\"o}rr, \{P. J.\} and Oostvogel, \{P. M.\}",

year = "2003",

month = jan,

doi = "10.1128/CDLI.10.1.174-176.2003",

language = "English",

volume = "10",

pages = "174--176",

journal = "Clinical and diagnostic laboratory immunology",

issn = "1071-412X",

publisher = "American Society for Microbiology",

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}

Comparison of serological assays for detection of Chlamydia trachomatis antibodies in different groups of obstetrical and gynecological patients. / Bax, C. J.; Mutsaers, J. A.E.M.; Jansen, C. L. et al.
In: Clinical and diagnostic laboratory immunology, Vol. 10, No. 1, 01.2003, p. 174-176.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Comparison of serological assays for detection of Chlamydia trachomatis antibodies in different groups of obstetrical and gynecological patients

AU - Bax, C. J.

AU - Mutsaers, J. A.E.M.

AU - Jansen, C. L.

AU - Trimbos, J. B.

AU - Dörr, P. J.

AU - Oostvogel, P. M.

PY - 2003/1

Y1 - 2003/1

N2 - New serological enzyme immunoassays (EIAs) were compared with microimmunofluorescence (MIF) as a "gold standard" to detect Chlamydia trachomatis antibodies in different groups of obstetrical, gynecological, and subfertile patients. There were no significant differences in seroprevalence rates, except for the group of C. trachomatis-positive patients (P < 0.01). Test characteristics were calculated for Chlamydia-EIA (Biologische Analysensystem GmbH, Lich, Germany) and pELISA (Medac, Wedel, Germany). pELISA seems to be a good alternative to MIF. It has high specificity and is easier to perform.

AB - New serological enzyme immunoassays (EIAs) were compared with microimmunofluorescence (MIF) as a "gold standard" to detect Chlamydia trachomatis antibodies in different groups of obstetrical, gynecological, and subfertile patients. There were no significant differences in seroprevalence rates, except for the group of C. trachomatis-positive patients (P < 0.01). Test characteristics were calculated for Chlamydia-EIA (Biologische Analysensystem GmbH, Lich, Germany) and pELISA (Medac, Wedel, Germany). pELISA seems to be a good alternative to MIF. It has high specificity and is easier to perform.

UR - https://www.scopus.com/pages/publications/0037246814

U2 - 10.1128/CDLI.10.1.174-176.2003

DO - 10.1128/CDLI.10.1.174-176.2003

M3 - Article

C2 - 12522057

SN - 1071-412X

VL - 10

SP - 174

EP - 176

JO - Clinical and diagnostic laboratory immunology

JF - Clinical and diagnostic laboratory immunology

IS - 1

ER -

Comparison of serological assays for detection of Chlamydia trachomatis antibodies in different groups of obstetrical and gynecological patients

Abstract

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