Comparative effects of two different calcipotriol (MC 903) cream formulations versus placebo in psoriasis vulgaris. A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Multi-Centre Study

Christine I. Harrington; David Goldin; Christopher R. Lovell; Peter Van De Kerkhof; Cees Nieboer; Joar Austad; Lars Molin; Birgitta Wilson Clareus; Eva Rask-Pedersen

doi:10.1111/j.1468-3083.1996.tb00159.x

Comparative effects of two different calcipotriol (MC 903) cream formulations versus placebo in psoriasis vulgaris. A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Multi-Centre Study

Christine I. Harrington^*
, David Goldin
, Christopher R. Lovell
, Peter Van De Kerkhof
, Cees Nieboer
, Joar Austad
, Lars Molin
, Birgitta Wilson Clareus
, Eva Rask-Pedersen

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background: Calcipotriol ointment is an effective treatment for psoriasis vulgaris. Although cream formulations have a less emollient effect they are often more acceptable to patients. Objective: To compare calcipotriol 50 μg/g in two different cream formulations with vehicle in patients with psoriasis vulgaris. Method: A randomised, double-blind, parallel group, multi-centre, comparison of cream A in which calcipotriol 50μg/g is dissolved, cream B in which calcipotriol 50 μg/g is suspended as fine particles and vehicle. A 2-week wash-out period was followed by 8 weeks double-blind treatment.

Original language	English
Pages (from-to)	152-158
Number of pages	7
Journal	Journal of the European Academy of Dermatology and Venereology
Volume	6
Issue number	2
DOIs	https://doi.org/10.1111/j.1468-3083.1996.tb00159.x
Publication status	Published - 1 Jan 1996

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1111/j.1468-3083.1996.tb00159.x

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Harrington, C. I., Goldin, D., Lovell, C. R., Van De Kerkhof, P., Nieboer, C., Austad, J., Molin, L., Clareus, B. W., & Rask-Pedersen, E. (1996). Comparative effects of two different calcipotriol (MC 903) cream formulations versus placebo in psoriasis vulgaris. A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Multi-Centre Study. Journal of the European Academy of Dermatology and Venereology, 6(2), 152-158. https://doi.org/10.1111/j.1468-3083.1996.tb00159.x

Harrington, Christine I. ; Goldin, David ; Lovell, Christopher R. et al. / Comparative effects of two different calcipotriol (MC 903) cream formulations versus placebo in psoriasis vulgaris. A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Multi-Centre Study. In: Journal of the European Academy of Dermatology and Venereology. 1996 ; Vol. 6, No. 2. pp. 152-158.

@article{9099a26c297f4aca9eb654c6398623a9,

title = "Comparative effects of two different calcipotriol (MC 903) cream formulations versus placebo in psoriasis vulgaris. A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Multi-Centre Study",

abstract = "Background: Calcipotriol ointment is an effective treatment for psoriasis vulgaris. Although cream formulations have a less emollient effect they are often more acceptable to patients. Objective: To compare calcipotriol 50 μg/g in two different cream formulations with vehicle in patients with psoriasis vulgaris. Method: A randomised, double-blind, parallel group, multi-centre, comparison of cream A in which calcipotriol 50μg/g is dissolved, cream B in which calcipotriol 50 μg/g is suspended as fine particles and vehicle. A 2-week wash-out period was followed by 8 weeks double-blind treatment.",

author = "Harrington, \{Christine I.\} and David Goldin and Lovell, \{Christopher R.\} and \{Van De Kerkhof\}, Peter and Cees Nieboer and Joar Austad and Lars Molin and Clareus, \{Birgitta Wilson\} and Eva Rask-Pedersen",

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doi = "10.1111/j.1468-3083.1996.tb00159.x",

language = "English",

volume = "6",

pages = "152--158",

journal = "Journal of the European Academy of Dermatology and Venereology",

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Harrington, CI, Goldin, D, Lovell, CR, Van De Kerkhof, P, Nieboer, C, Austad, J, Molin, L, Clareus, BW & Rask-Pedersen, E 1996, 'Comparative effects of two different calcipotriol (MC 903) cream formulations versus placebo in psoriasis vulgaris. A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Multi-Centre Study', Journal of the European Academy of Dermatology and Venereology, vol. 6, no. 2, pp. 152-158. https://doi.org/10.1111/j.1468-3083.1996.tb00159.x

Comparative effects of two different calcipotriol (MC 903) cream formulations versus placebo in psoriasis vulgaris. A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Multi-Centre Study. / Harrington, Christine I.; Goldin, David; Lovell, Christopher R. et al.
In: Journal of the European Academy of Dermatology and Venereology, Vol. 6, No. 2, 01.01.1996, p. 152-158.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Comparative effects of two different calcipotriol (MC 903) cream formulations versus placebo in psoriasis vulgaris. A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Multi-Centre Study

AU - Harrington, Christine I.

AU - Goldin, David

AU - Lovell, Christopher R.

AU - Van De Kerkhof, Peter

AU - Nieboer, Cees

AU - Austad, Joar

AU - Molin, Lars

AU - Clareus, Birgitta Wilson

AU - Rask-Pedersen, Eva

PY - 1996/1/1

Y1 - 1996/1/1

N2 - Background: Calcipotriol ointment is an effective treatment for psoriasis vulgaris. Although cream formulations have a less emollient effect they are often more acceptable to patients. Objective: To compare calcipotriol 50 μg/g in two different cream formulations with vehicle in patients with psoriasis vulgaris. Method: A randomised, double-blind, parallel group, multi-centre, comparison of cream A in which calcipotriol 50μg/g is dissolved, cream B in which calcipotriol 50 μg/g is suspended as fine particles and vehicle. A 2-week wash-out period was followed by 8 weeks double-blind treatment.

AB - Background: Calcipotriol ointment is an effective treatment for psoriasis vulgaris. Although cream formulations have a less emollient effect they are often more acceptable to patients. Objective: To compare calcipotriol 50 μg/g in two different cream formulations with vehicle in patients with psoriasis vulgaris. Method: A randomised, double-blind, parallel group, multi-centre, comparison of cream A in which calcipotriol 50μg/g is dissolved, cream B in which calcipotriol 50 μg/g is suspended as fine particles and vehicle. A 2-week wash-out period was followed by 8 weeks double-blind treatment.

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U2 - 10.1111/j.1468-3083.1996.tb00159.x

DO - 10.1111/j.1468-3083.1996.tb00159.x

M3 - Article

SN - 0926-9959

VL - 6

SP - 152

EP - 158

JO - Journal of the European Academy of Dermatology and Venereology

JF - Journal of the European Academy of Dermatology and Venereology

IS - 2

ER -

Harrington CI, Goldin D, Lovell CR, Van De Kerkhof P, Nieboer C, Austad J et al. Comparative effects of two different calcipotriol (MC 903) cream formulations versus placebo in psoriasis vulgaris. A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Multi-Centre Study. Journal of the European Academy of Dermatology and Venereology. 1996 Jan 1;6(2):152-158. doi: 10.1111/j.1468-3083.1996.tb00159.x

Comparative effects of two different calcipotriol (MC 903) cream formulations versus placebo in psoriasis vulgaris. A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Multi-Centre Study

Abstract

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