Clozapine-induced agranulocytosis: A case report immunopathophysiological considerations

A. A. Van De Loosdrecht; H. J. Faber; P. Hordijk; D. R.A. Uges; A. Smit

doi:10.1016/S0300-2977(97)00074-0

Clozapine-induced agranulocytosis: A case report immunopathophysiological considerations

A. A. Van De Loosdrecht
, H. J. Faber
, P. Hordijk
, D. R.A. Uges
, A. Smit

University of Groningen

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A 46-year-old woman is described with a clozapine-induced agranulocytosis. She was the treated with a broad-spectrum antibiotic and supportive care was provided with granulocyte colony-stimulating factor (G- CSF). Immune-mediated mechanisms of clozapine-induced agranulocytosis and the role of haematopoietic growth factors are discussed.

Original language	English
Pages (from-to)	26-29
Number of pages	4
Journal	Netherlands journal of medicine
Volume	52
Issue number	1
DOIs	https://doi.org/10.1016/S0300-2977(97)00074-0
Publication status	Published - Jan 1998

Keywords

Agranulocytosis
Clozapine
Granulocyte colony stimulating factor

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10.1016/S0300-2977(97)00074-0

Cite this

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title = "Clozapine-induced agranulocytosis: A case report immunopathophysiological considerations",

abstract = "A 46-year-old woman is described with a clozapine-induced agranulocytosis. She was the treated with a broad-spectrum antibiotic and supportive care was provided with granulocyte colony-stimulating factor (G- CSF). Immune-mediated mechanisms of clozapine-induced agranulocytosis and the role of haematopoietic growth factors are discussed.",

keywords = "Agranulocytosis, Clozapine, Granulocyte colony stimulating factor",

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AU - Hordijk, P.

AU - Uges, D. R.A.

AU - Smit, A.

PY - 1998/1

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AB - A 46-year-old woman is described with a clozapine-induced agranulocytosis. She was the treated with a broad-spectrum antibiotic and supportive care was provided with granulocyte colony-stimulating factor (G- CSF). Immune-mediated mechanisms of clozapine-induced agranulocytosis and the role of haematopoietic growth factors are discussed.

KW - Agranulocytosis

KW - Clozapine

KW - Granulocyte colony stimulating factor

UR - https://www.scopus.com/pages/publications/0031893755

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DO - 10.1016/S0300-2977(97)00074-0

M3 - Article

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SP - 26

EP - 29

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JF - Netherlands journal of medicine

IS - 1

ER -

Clozapine-induced agranulocytosis: A case report immunopathophysiological considerations

Abstract

Keywords

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