Charting vascular development: Junctional landscapes guiding endothelial migration and signaling routes to capillary malformations

This thesis dissects how endothelial cells build, remodel, and sometimes corrupt the vascular network, linking vascular morphogenesis to human vascular disease.
First, it interrogates asymmetric adherens junctions (AAJs), an adhesive molecular structure that forms at leader-follower interfaces in migrating