Cardiovasculaire en gastro-intestinale veiligheid van NSAID's

Patricia M. L. A. van den Bemt; Eric T. T. L. Tjwa; Martijn G. H. van Oijen

Cardiovasculaire en gastro-intestinale veiligheid van NSAID's

Patricia M. L. A. van den Bemt, Eric T. T. L. Tjwa, Martijn G. H. van Oijen

pre-AMC

Research output: Contribution to journal › Article › Professional

2 Citations (Scopus)

Abstract

All NSAIDs may induce cardiotoxicity. In this respect naproxen is relatively the safest choice. Selective cyclo-oxygenase-2-inhibitors (coxibs) are at least as effective in preventing clinically relevant gastrointestinal toxicity as non-selective NSAIDs plus a protonpump inhibitor (PPI). Non-selective NSAIDs plus a PPI are more effective in prevention of dyspepsia than coxibs. After a serious gastrointestinal complication while using NSAIDs, in principal the patient should no longer use NSAIDs. If needed, a coxib plus a PPI is the first choice

Original language	Dutch
Pages (from-to)	A7311
Journal	Nederlands tijdschrift voor geneeskunde
Volume	158
Publication status	Published - 2014
Externally published	Yes

Cite this

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title = "Cardiovasculaire en gastro-intestinale veiligheid van NSAID's",

abstract = "All NSAIDs may induce cardiotoxicity. In this respect naproxen is relatively the safest choice. Selective cyclo-oxygenase-2-inhibitors (coxibs) are at least as effective in preventing clinically relevant gastrointestinal toxicity as non-selective NSAIDs plus a protonpump inhibitor (PPI). Non-selective NSAIDs plus a PPI are more effective in prevention of dyspepsia than coxibs. After a serious gastrointestinal complication while using NSAIDs, in principal the patient should no longer use NSAIDs. If needed, a coxib plus a PPI is the first choice",

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journal = "Nederlands tijdschrift voor geneeskunde",

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AU - Tjwa, Eric T. T. L.

AU - van Oijen, Martijn G. H.

PY - 2014

Y1 - 2014

N2 - All NSAIDs may induce cardiotoxicity. In this respect naproxen is relatively the safest choice. Selective cyclo-oxygenase-2-inhibitors (coxibs) are at least as effective in preventing clinically relevant gastrointestinal toxicity as non-selective NSAIDs plus a protonpump inhibitor (PPI). Non-selective NSAIDs plus a PPI are more effective in prevention of dyspepsia than coxibs. After a serious gastrointestinal complication while using NSAIDs, in principal the patient should no longer use NSAIDs. If needed, a coxib plus a PPI is the first choice

AB - All NSAIDs may induce cardiotoxicity. In this respect naproxen is relatively the safest choice. Selective cyclo-oxygenase-2-inhibitors (coxibs) are at least as effective in preventing clinically relevant gastrointestinal toxicity as non-selective NSAIDs plus a protonpump inhibitor (PPI). Non-selective NSAIDs plus a PPI are more effective in prevention of dyspepsia than coxibs. After a serious gastrointestinal complication while using NSAIDs, in principal the patient should no longer use NSAIDs. If needed, a coxib plus a PPI is the first choice

M3 - Article

C2 - 24713339

SN - 0028-2162

VL - 158

SP - A7311

JO - Nederlands tijdschrift voor geneeskunde

JF - Nederlands tijdschrift voor geneeskunde

ER -