Cardiac contractility modulation signals improve exercise intolerance and maladaptive regulation of cardiac key proteins for systolic and diastolic function in HFpEF

Carsten Tschöpe; Sophie Van Linthout; Frank Spillmann; Oliver Klein; Sebastian Biewener; Andrew Remppis; David Gutterman; Wolfgang A Linke; Burkert Pieske; Nazha Hamdani; Mattias Roser

doi:10.1016/j.ijcard.2015.10.208

Cardiac contractility modulation signals improve exercise intolerance and maladaptive regulation of cardiac key proteins for systolic and diastolic function in HFpEF

Carsten Tschöpe
, Sophie Van Linthout
, Frank Spillmann
, Oliver Klein
, Sebastian Biewener
, Andrew Remppis
, David Gutterman
, Wolfgang A Linke
, Burkert Pieske
, Nazha Hamdani
, Mattias Roser

Charité-University-Medicine Berlin, Campus Rudolf Virchow, Department of Cardiology, Berlin, Germany; Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Berlin, Germany; DZHK (German Center for Cardiovascular Research), partner site Berlin, Germany. Electronic address: [email protected].
Charité-University-Medicine Berlin, Campus Rudolf Virchow, Department of Cardiology, Berlin, Germany; Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Berlin, Germany; DZHK (German Center for Cardiovascular Research), partner site Berlin, Germany.
Charité-University-Medicine Berlin, Campus Rudolf Virchow, Department of Cardiology, Berlin, Germany.
Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Berlin, Germany.
Charité-University-Medicine Berlin, Campus Benjamin Franklin, Department of Cardiology, Berlin, German.
Heart and Vascular Center (HGZ), Bad Bevensen, Germany.
Radiation Oncology, Froedtert and Medical College of Wisconsin , Milwaukee, WI , USA.
From the Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands (C.F., J.K., R.M., N.H., W.J.P.); and Department of Cardiovascular Physiology, Ruhr University Bochum, Germany (N.H.).
Charité-University-Medicine Berlin, Campus Rudolf Virchow, Department of Cardiology, Berlin, Germany; DZHK (German Center for Cardiovascular Research), partner site Berlin, Germany; Department of Cardiology, Deutsches Herzzentrum Berlin (DHZB), Berlin, Germany.

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	1061-6
Number of pages	6
Journal	International journal of cardiology
Volume	203
DOIs	https://doi.org/10.1016/j.ijcard.2015.10.208
Publication status	Published - 15 Jan 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Calcium
Connectin
Electric Stimulation
Exercise Test
Exercise Tolerance
Female
Heart Failure
Humans
Middle Aged
Myocardial Contraction
Myocardium
Prospective Studies
Proteomics
Quality of Life
Stroke Volume
Ventricular Remodeling
Case Reports
Letter

Access to Document

10.1016/j.ijcard.2015.10.208

Cite this

Tschöpe, C., Van Linthout, S., Spillmann, F., Klein, O., Biewener, S., Remppis, A., Gutterman, D., Linke, W. A., Pieske, B., Hamdani, N., & Roser, M. (2016). Cardiac contractility modulation signals improve exercise intolerance and maladaptive regulation of cardiac key proteins for systolic and diastolic function in HFpEF. International journal of cardiology, 203, 1061-6. https://doi.org/10.1016/j.ijcard.2015.10.208

@article{770732e1a9954879a8dee26253eec73b,

title = "Cardiac contractility modulation signals improve exercise intolerance and maladaptive regulation of cardiac key proteins for systolic and diastolic function in HFpEF",

keywords = "Calcium, Connectin, Electric Stimulation, Exercise Test, Exercise Tolerance, Female, Heart Failure, Humans, Middle Aged, Myocardial Contraction, Myocardium, Prospective Studies, Proteomics, Quality of Life, Stroke Volume, Ventricular Remodeling, Case Reports, Letter",

author = "Carsten Tsch{\"o}pe and \{Van Linthout\}, Sophie and Frank Spillmann and Oliver Klein and Sebastian Biewener and Andrew Remppis and David Gutterman and Linke, \{Wolfgang A\} and Burkert Pieske and Nazha Hamdani and Mattias Roser",

year = "2016",

month = jan,

day = "15",

doi = "10.1016/j.ijcard.2015.10.208",

language = "English",

volume = "203",

pages = "1061--6",

journal = "International journal of cardiology",

issn = "0167-5273",

publisher = "Elsevier Ireland Ltd",

}

Tschöpe, C, Van Linthout, S, Spillmann, F, Klein, O, Biewener, S, Remppis, A, Gutterman, D, Linke, WA, Pieske, B, Hamdani, N & Roser, M 2016, 'Cardiac contractility modulation signals improve exercise intolerance and maladaptive regulation of cardiac key proteins for systolic and diastolic function in HFpEF', International journal of cardiology, vol. 203, pp. 1061-6. https://doi.org/10.1016/j.ijcard.2015.10.208

Cardiac contractility modulation signals improve exercise intolerance and maladaptive regulation of cardiac key proteins for systolic and diastolic function in HFpEF. / Tschöpe, Carsten; Van Linthout, Sophie; Spillmann, Frank et al.
In: International journal of cardiology, Vol. 203, 15.01.2016, p. 1061-6.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Cardiac contractility modulation signals improve exercise intolerance and maladaptive regulation of cardiac key proteins for systolic and diastolic function in HFpEF

AU - Tschöpe, Carsten

AU - Van Linthout, Sophie

AU - Spillmann, Frank

AU - Klein, Oliver

AU - Biewener, Sebastian

AU - Remppis, Andrew

AU - Gutterman, David

AU - Linke, Wolfgang A

AU - Pieske, Burkert

AU - Hamdani, Nazha

AU - Roser, Mattias

PY - 2016/1/15

Y1 - 2016/1/15

KW - Calcium

KW - Connectin

KW - Electric Stimulation

KW - Exercise Test

KW - Exercise Tolerance

KW - Female

KW - Heart Failure

KW - Humans

KW - Middle Aged

KW - Myocardial Contraction

KW - Myocardium

KW - Prospective Studies

KW - Proteomics

KW - Quality of Life

KW - Stroke Volume

KW - Ventricular Remodeling

KW - Case Reports

KW - Letter

U2 - 10.1016/j.ijcard.2015.10.208

DO - 10.1016/j.ijcard.2015.10.208

M3 - Article

SN - 0167-5273

VL - 203

SP - 1061

EP - 1066

JO - International journal of cardiology

JF - International journal of cardiology

ER -