Abstract
A recent article in Proceedings of the National Academy of Sciences investigated γδ T cell antigen specificity in mice and humans, in which the authors show that γδ T cell antigen specificity is not constrained to one epitope. Rather, γδ T cells recognize a broad range of diverse antigens containing similar chemical structures or properties. In this News and Views, the importance of γδ T cell antigen polyspecificity during immune responses is highlighted.
| Original language | English |
|---|---|
| Pages (from-to) | 794-796 |
| Number of pages | 3 |
| Journal | Journal of Leukocyte Biology |
| Volume | 115 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 29 Apr 2024 |
| Externally published | Yes |
Keywords
- Receptors, Antigen, T-Cell, gamma-delta/immunology
- Animals
- Humans
- T-Lymphocytes/immunology
- Mice
- Antigens/immunology
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