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Beyond static measurements: dynamic frailty improves survival prediction in multiple myeloma

  • F Smits
  • , Kaz Groen
  • , Mark-David Levin
  • , Claudia Stege
  • , Roel J W van Kampen
  • , Ellen van der Spek
  • , Yavuz M Bilgin
  • , Noortje Thielen
  • , Inger S Nijhof
  • , Inge Ludwig
  • , Esther G M de Waal
  • , Yorick Sandberg
  • , Alain Kentos
  • , Gert-Jan Timmers
  • , Josien C Regelink
  • , Matthijs Westerman
  • , Koen de Heer
  • , Marie-Christiane Mb Vekemans
  • , Nazik Durdu-Rayman
  • , Nicole C H P de Graauw
  • Maarten R Seefat, Niels W C J van de Donk, Paula F Ypma, Kazem Nasserinejad, Sonja Zweegman
  • Albert Schweitzer Hospital
  • Zuyerland Medical Center
  • Rijnstate
  • ADRZ
  • Bernhoven Hospital
  • Medical Center Leeuwarden
  • Maasstad Hospital
  • Centre Hospitalier Jolimont
  • UCL Cliniques universitaires Saint-Luc
  • Franciscus Hospital
  • Bravis Hospital
  • Haga Hospital

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

The level of frailty, according to the IMWG frailty index, is highly dynamic during anti-myeloma treatment. Dynamic frailty assessment improved the prediction of survival and early mortality as compared to the prognostic value of static frailty level at baseline. HOVON 143: NTR6297 HOVON 123: NTR4244.

Original languageEnglish
JournalBlood
DOIs
Publication statusE-pub ahead of print - 22 Nov 2024

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