Atg5: more than an autophagy factor

Patrice Codogno; Alfred J. Meijer

doi:10.1038/ncb1006-1045

Atg5: more than an autophagy factor

Patrice Codogno
, Alfred J. Meijer

Research output: Contribution to journal › Editorial › Academic › peer-review

Abstract

Atg5 has been previously characterized as a protein specifically required for autophagy, a lysosomal catabolic pathway for proteins and organelles. However, it has now been shown that, in addition to its role in the formation of autophagosomes, an Atg5 fragment produced by calpain cleavage has pro-apoptotic properties

Original language	English
Pages (from-to)	1045-1047
Journal	Nature cell biology
Volume	8
Issue number	10
DOIs	https://doi.org/10.1038/ncb1006-1045
Publication status	Published - 2006

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title = "Atg5: more than an autophagy factor",

abstract = "Atg5 has been previously characterized as a protein specifically required for autophagy, a lysosomal catabolic pathway for proteins and organelles. However, it has now been shown that, in addition to its role in the formation of autophagosomes, an Atg5 fragment produced by calpain cleavage has pro-apoptotic properties",

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year = "2006",

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AB - Atg5 has been previously characterized as a protein specifically required for autophagy, a lysosomal catabolic pathway for proteins and organelles. However, it has now been shown that, in addition to its role in the formation of autophagosomes, an Atg5 fragment produced by calpain cleavage has pro-apoptotic properties

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DO - 10.1038/ncb1006-1045

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SN - 1465-7392

VL - 8

SP - 1045

EP - 1047

JO - Nature cell biology

JF - Nature cell biology

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Atg5: more than an autophagy factor

Abstract

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