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Assessment of heart rate circadianity alterations in patients with depression using a wearable device

  • Sofia Perez Gracia*
  • , Sara Siddi
  • , Nicholas Cummins
  • , Srinivasan Vairavan
  • , Faith Matcham
  • , Josep Maria Haro
  • , Matthew Hotopf
  • , Femke Lamers
  • , Brenda Penninx
  • , Richard Dobson
  • , Vaibhav Narayan
  • , Raquel Bailon
  • , Alba Martin Yebra
  • *Corresponding author for this work
  • University of Zaragoza
  • Parc Sanitari Sant Joan de Déu
  • King's College London
  • Janssen R&D
  • University of Sussex
  • IR Sant Joan de Deu CIBERSAM

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

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Abstract

The aim of this study is to assess whether the possible loss of circadian rhythm, a modulator of heart rate, is associated with the severity of depression. For that, Cosinor fitting method was applied to heart rate data of 203 patients with major depressive disorder, recorded continuously over 18 months by a wearable device. Results revealed that the amplitude derived from the Cosinor fit is significantly lower in patients with severe depression, implying a loss in circadian rhythmicity when depression is severe.

Original languageEnglish
Title of host publication2024 13th Conference of the European Study Group on Cardiovascular Oscillations
Subtitle of host publicationPhysiologically-Guided Signal Processing of Cardiovascular and Cerebrovascular Oscillations, ESGCO 2024
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9798350392050
DOIs
Publication statusPublished - 2024
Event13th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2024 - Zaragoza, Spain
Duration: 23 Oct 202425 Oct 2024

Publication series

Name2024 13th Conference of the European Study Group on Cardiovascular Oscillations: Physiologically-Guided Signal Processing of Cardiovascular and Cerebrovascular Oscillations, ESGCO 2024

Conference

Conference13th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2024
Country/TerritorySpain
CityZaragoza
Period23/10/202425/10/2024

Keywords

  • circadian rhythm
  • Cosinor analysis
  • depression
  • heart rate
  • wearable device

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