Skip to main navigation Skip to search Skip to main content

Artemisinin drugs in the treatment of malaria: From medicinal herb to registered medication

  • Amsterdam UMC - University of Amsterdam
  • University of Amsterdam

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Registration in Europe of several artemisinin drugs for the treatment of malaria can soon be expected. Artemisinin is isolated from the herb Artemisia annua, in use in China more than 2000 years as a herbal tea against fever. Artemisinin drugs are being used extensively in South-East Asia and increasingly in Africa. Active derivatives have been synthesized artemether, arteether and artesunate - which are used for oral, intramuscular, rectal and intravenous administration. The origin, mechanism of action, efficacy and safety in patients, the pharmacokinetics and the position of this group of compounds among existing antimalarials are discussed in this review.
Original languageEnglish
Pages (from-to)199-205
Number of pages7
JournalTrends in pharmacological sciences
Volume20
Issue number5
DOIs
Publication statusPublished - 1 May 1999

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Fingerprint

Dive into the research topics of 'Artemisinin drugs in the treatment of malaria: From medicinal herb to registered medication'. Together they form a unique fingerprint.

Cite this