@inproceedings{a1cd56fb999f4beda81cd78b837bdb4e,
title = "Analysis of doxycycline effects on C.elegans mitochondrial stress and neurodegeneration within a microfluidic {"}smart-plate{"}",
abstract = "We present a microfluidic {"}smart-plate{"} technology for C.elegans research and employ it for a detailed characterization of the effects of doxycycline on mitochondrial stress and protein aggregation in an amyotrophic lateral sclerosis (ALS) worm model; our work is a prototypical feasibility study of pharmacological screens targeting early ALS modifiers.",
keywords = "Amyotrophic lateral sclerosis (ALS), Caenorhabditis elegans, Doxycycline, Microfluidics, Mitochondrial stress, Neurodegenerative disease",
author = "M. Cornaglia and L. Mouchiroud and G. Krishnamani and V. Sorrentino and T. Lehnert and J. Auwerx and Gijs, \{M. A.M.\}",
year = "2016",
language = "English",
series = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
publisher = "Chemical and Biological Microsystems Society",
pages = "467--468",
booktitle = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
note = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 ; Conference date: 09-10-2016 Through 13-10-2016",
}