An additive opinion to the committee opinion of ASRM and SART on the use of preimplantation genetic testing for aneuploidy (PGT-A)

Norbert Gleicher; David H. Barad; Pasquale Patrizio; Sonya Gayete-Lafuente; Andrea Weghofer; Zion Ben Rafael; Shizuko Takahashi; Demián Glujovsky; Ben W. Mol; Raoul Orvieto

doi:10.1007/s10815-024-03318-z

An additive opinion to the committee opinion of ASRM and SART on the use of preimplantation genetic testing for aneuploidy (PGT-A)

Norbert Gleicher
, David H. Barad^*
, Pasquale Patrizio
, Sonya Gayete-Lafuente
, Andrea Weghofer
, Zion Ben Rafael
, Shizuko Takahashi
, Demián Glujovsky
, Ben W. Mol
, Raoul Orvieto

^*Corresponding author for this work

Center for Human Reproduction (CHR)
Foundation for Reproductive Medicine, New York
Rockefeller University
Medical University of Vienna
University of Miami
Sanz Medical Center-Laniado Hospital Israel
National University of Singapore
Centro de Estudios en Ginecología y Reproducción, Buenos Aires
Monash University
Sheba Medical Center at Tel Hashomer
Tel Aviv University

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

After over 20 years of progressively increasing clinical utilization of PGT-A (and its precursors), the American Society for Reproductive Medicine (ASRM) and its daughter society, the Society for Assisted Reproduction (SART), for the first time published a committee opinion clearly acknowledging that “the value of PGT-A as a routine screening test for patients undergoing in vitro fertilization (IVF) has not been demonstrated.” This statement is timely and welcome but requires some additions and raises some new questions, among those why, if PGT-A in a general population does not improve IVF cycle outcomes, the routine clinical utilization of PGT-A should continue.

Original language	English
Journal	Journal of assisted reproduction and genetics
DOIs	https://doi.org/10.1007/s10815-024-03318-z
Publication status	E-pub ahead of print - 2024
Externally published	Yes

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Gleicher, N., Barad, D. H., Patrizio, P., Gayete-Lafuente, S., Weghofer, A., Rafael, Z. B., Takahashi, S., Glujovsky, D., Mol, B. W., & Orvieto, R. (2024). An additive opinion to the committee opinion of ASRM and SART on the use of preimplantation genetic testing for aneuploidy (PGT-A). Journal of assisted reproduction and genetics. Advance online publication. https://doi.org/10.1007/s10815-024-03318-z

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title = "An additive opinion to the committee opinion of ASRM and SART on the use of preimplantation genetic testing for aneuploidy (PGT-A)",

abstract = "After over 20 years of progressively increasing clinical utilization of PGT-A (and its precursors), the American Society for Reproductive Medicine (ASRM) and its daughter society, the Society for Assisted Reproduction (SART), for the first time published a committee opinion clearly acknowledging that {\textquotedblleft}the value of PGT-A as a routine screening test for patients undergoing in vitro fertilization (IVF) has not been demonstrated.{\textquotedblright} This statement is timely and welcome but requires some additions and raises some new questions, among those why, if PGT-A in a general population does not improve IVF cycle outcomes, the routine clinical utilization of PGT-A should continue.",

author = "Norbert Gleicher and Barad, \{David H.\} and Pasquale Patrizio and Sonya Gayete-Lafuente and Andrea Weghofer and Rafael, \{Zion Ben\} and Shizuko Takahashi and Demi{\'a}n Glujovsky and Mol, \{Ben W.\} and Raoul Orvieto",

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T1 - An additive opinion to the committee opinion of ASRM and SART on the use of preimplantation genetic testing for aneuploidy (PGT-A)

AU - Gleicher, Norbert

AU - Barad, David H.

AU - Patrizio, Pasquale

AU - Gayete-Lafuente, Sonya

AU - Weghofer, Andrea

AU - Rafael, Zion Ben

AU - Takahashi, Shizuko

AU - Glujovsky, Demián

AU - Mol, Ben W.

AU - Orvieto, Raoul

PY - 2024

Y1 - 2024

N2 - After over 20 years of progressively increasing clinical utilization of PGT-A (and its precursors), the American Society for Reproductive Medicine (ASRM) and its daughter society, the Society for Assisted Reproduction (SART), for the first time published a committee opinion clearly acknowledging that “the value of PGT-A as a routine screening test for patients undergoing in vitro fertilization (IVF) has not been demonstrated.” This statement is timely and welcome but requires some additions and raises some new questions, among those why, if PGT-A in a general population does not improve IVF cycle outcomes, the routine clinical utilization of PGT-A should continue.

AB - After over 20 years of progressively increasing clinical utilization of PGT-A (and its precursors), the American Society for Reproductive Medicine (ASRM) and its daughter society, the Society for Assisted Reproduction (SART), for the first time published a committee opinion clearly acknowledging that “the value of PGT-A as a routine screening test for patients undergoing in vitro fertilization (IVF) has not been demonstrated.” This statement is timely and welcome but requires some additions and raises some new questions, among those why, if PGT-A in a general population does not improve IVF cycle outcomes, the routine clinical utilization of PGT-A should continue.

UR - https://www.scopus.com/pages/publications/85212471497

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DO - 10.1007/s10815-024-03318-z

M3 - Article

C2 - 39693036

SN - 1058-0468

JO - Journal of assisted reproduction and genetics

JF - Journal of assisted reproduction and genetics

ER -

An additive opinion to the committee opinion of ASRM and SART on the use of preimplantation genetic testing for aneuploidy (PGT-A)

Abstract

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