Advances in cancer imaging require renewed radiotherapy dose and target volume concepts

Johannes H.A.M. Kaanders; Sven van den Bosch; Tim Dijkema; Abrahim Al-Mamgani; Cornelis P.J. Raaijmakers; Wouter V. Vogel

doi:10.1016/j.radonc.2020.04.016

Advances in cancer imaging require renewed radiotherapy dose and target volume concepts

Johannes H.A.M. Kaanders^*
, Sven van den Bosch
, Tim Dijkema
, Abrahim Al-Mamgani
, Cornelis P.J. Raaijmakers
, Wouter V. Vogel

^*Corresponding author for this work

Radboud University Nijmegen
Department of Radiation Oncology
Netherlands Cancer Institute
University Medical Center Utrecht
Utrecht University
Department of Nuclear Medicine

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Advances in diagnostic imaging create opportunities for improved therapeutic targeting of cancer but conceptual thinking about radiotherapy target volume definition and dose-prescription is not keeping up. In this opinion paper we discuss how modern imaging can contribute to new concepts for radiotherapy dose-prescription and target volume definition illustrated by the example of head and neck cancer. These new insights have the potential to significantly reduce radiation associated toxicity and may have important impact on the combination of radiotherapy with systemic cancer therapies.

Original language	English
Pages (from-to)	140-142
Number of pages	3
Journal	Radiotherapy and oncology
Volume	148
DOIs	https://doi.org/10.1016/j.radonc.2020.04.016
Publication status	Published - Jul 2020
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Dose
Head and Neck cancer
Imaging
Radiotherapy
Target volume

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10.1016/j.radonc.2020.04.016

Cite this

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title = "Advances in cancer imaging require renewed radiotherapy dose and target volume concepts",

abstract = "Advances in diagnostic imaging create opportunities for improved therapeutic targeting of cancer but conceptual thinking about radiotherapy target volume definition and dose-prescription is not keeping up. In this opinion paper we discuss how modern imaging can contribute to new concepts for radiotherapy dose-prescription and target volume definition illustrated by the example of head and neck cancer. These new insights have the potential to significantly reduce radiation associated toxicity and may have important impact on the combination of radiotherapy with systemic cancer therapies.",

keywords = "Dose, Head and Neck cancer, Imaging, Radiotherapy, Target volume",

author = "Kaanders, \{Johannes H.A.M.\} and \{van den Bosch\}, Sven and Tim Dijkema and Abrahim Al-Mamgani and Raaijmakers, \{Cornelis P.J.\} and Vogel, \{Wouter V.\}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier B.V.",

year = "2020",

month = jul,

doi = "10.1016/j.radonc.2020.04.016",

language = "English",

volume = "148",

pages = "140--142",

journal = "Radiotherapy and oncology",

issn = "0167-8140",

publisher = "Elsevier Ireland Ltd",

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TY - JOUR

T1 - Advances in cancer imaging require renewed radiotherapy dose and target volume concepts

AU - Kaanders, Johannes H.A.M.

AU - van den Bosch, Sven

AU - Dijkema, Tim

AU - Al-Mamgani, Abrahim

AU - Raaijmakers, Cornelis P.J.

AU - Vogel, Wouter V.

PY - 2020/7

Y1 - 2020/7

N2 - Advances in diagnostic imaging create opportunities for improved therapeutic targeting of cancer but conceptual thinking about radiotherapy target volume definition and dose-prescription is not keeping up. In this opinion paper we discuss how modern imaging can contribute to new concepts for radiotherapy dose-prescription and target volume definition illustrated by the example of head and neck cancer. These new insights have the potential to significantly reduce radiation associated toxicity and may have important impact on the combination of radiotherapy with systemic cancer therapies.

AB - Advances in diagnostic imaging create opportunities for improved therapeutic targeting of cancer but conceptual thinking about radiotherapy target volume definition and dose-prescription is not keeping up. In this opinion paper we discuss how modern imaging can contribute to new concepts for radiotherapy dose-prescription and target volume definition illustrated by the example of head and neck cancer. These new insights have the potential to significantly reduce radiation associated toxicity and may have important impact on the combination of radiotherapy with systemic cancer therapies.

KW - Dose

KW - Head and Neck cancer

KW - Imaging

KW - Radiotherapy

KW - Target volume

UR - https://www.scopus.com/pages/publications/85083885111

U2 - 10.1016/j.radonc.2020.04.016

DO - 10.1016/j.radonc.2020.04.016

M3 - Article

C2 - 32361663

AN - SCOPUS:85083885111

SN - 0167-8140

VL - 148

SP - 140

EP - 142

JO - Radiotherapy and oncology

JF - Radiotherapy and oncology

ER -

Advances in cancer imaging require renewed radiotherapy dose and target volume concepts

Abstract

UN SDGs

Keywords

Access to Document

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