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Adaptive Magnetic Resonance-Guided Stereotactic Body Radiotherapy: The Next Step in the Treatment of Renal Cell Carcinoma

  • Brian Keller
  • , Anna M. E. Bruynzeel
  • , Chad Tang
  • , Anand Swaminath
  • , Linda Kerkmeijer
  • , William Chu*
  • *Corresponding author for this work
  • University of Toronto
  • Amsterdam UMC - University of Amsterdam
  • University of Texas MD Anderson Cancer Center
  • McMaster University
  • Radboud University Medical Center
  • Radboud University Nijmegen

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Adaptive MR-guided radiotherapy (MRgRT) is a new treatment paradigm and its role as a non-invasive treatment option for renal cell carcinoma is evolving. The early clinical experience to date shows that real-time plan adaptation based on the daily MRI anatomy can lead to improved target coverage and normal tissue sparing. Continued technological innovations will further mitigate the challenges of organ motion and enable more advanced treatment adaptation, and potentially lead to enhanced oncologic outcomes and preservation of renal function. Future applications look promising to make a positive clinical impact and further the personalization of radiotherapy in the management of renal cell carcinoma.
Original languageEnglish
Article number634830
JournalFrontiers in oncology
Volume11
DOIs
Publication statusPublished - 11 May 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • image-guided radiotherapy
  • MR-guided radiotherapy
  • MR-linac
  • renal cell carcinoma
  • stereotactic body radiotherapy

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