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Activation of cytotoxic lymphocytes in patients with scrub typhus

  • Maaike de Fost
  • , Wirongrong Chierakul
  • , Kriangsak Pimda
  • , Arjen M. Dondorp
  • , Nicholas J. White
  • , Tom van der Poll

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Thai patients with scrub typhus caused by the intracellular pathogen Orientia tsutsugamushi displayed elevated plasma concentrations of granzymes A and B, interferon-gamma (IFN)-gamma-inducible protein 10, and monokine induced by IFN-gamma. These data suggest that activation of cytotoxic lymphocytes is part of the early host response to scrub typhus
Original languageEnglish
Pages (from-to)465-467
JournalAmerican journal of tropical medicine and hygiene
Volume72
Issue number4
Publication statusPublished - 2005

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