Absolute level of Epstein-Barr virus DNA in human immunodeficiency virus type 1 infection is not predictive of AIDS-related non-Hodgkin lymphoma

Debbie van Baarle; Katja C. Wolthers; Egbert Hovenkamp; Hubert G. M. Niesters; Albert D. M. E. Osterhaus; Frank Miedema; Marinus H. J. van Oers

doi:10.1086/341460

Absolute level of Epstein-Barr virus DNA in human immunodeficiency virus type 1 infection is not predictive of AIDS-related non-Hodgkin lymphoma

Debbie van Baarle
, Katja C. Wolthers
, Egbert Hovenkamp
, Hubert G. M. Niesters
, Albert D. M. E. Osterhaus
, Frank Miedema
, Marinus H. J. van Oers

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

To study whether Epstein-Barr virus (EBV) load can be used to predict the occurrence of acquired immunodeficiency syndrome-related non-Hodgkin lymphoma (AIDS-NHL), we determined EBV load longitudinally for individuals infected with human immunodeficiency virus type 1. EBV load in peripheral blood mononuclear cells (PBMC) was high and displayed considerable fluctuations over time, indicating that absolute EBV load in PBMC is not predictive of the development of AIDS-NHL. EBV DNA was also detectable in serum at some time points but at a lower level

Original language	English
Pages (from-to)	405-409
Journal	Journal of infectious diseases
Volume	186
Issue number	3
DOIs	https://doi.org/10.1086/341460
Publication status	Published - 2002

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SDG 3 Good Health and Well-being

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10.1086/341460

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title = "Absolute level of Epstein-Barr virus DNA in human immunodeficiency virus type 1 infection is not predictive of AIDS-related non-Hodgkin lymphoma",

abstract = "To study whether Epstein-Barr virus (EBV) load can be used to predict the occurrence of acquired immunodeficiency syndrome-related non-Hodgkin lymphoma (AIDS-NHL), we determined EBV load longitudinally for individuals infected with human immunodeficiency virus type 1. EBV load in peripheral blood mononuclear cells (PBMC) was high and displayed considerable fluctuations over time, indicating that absolute EBV load in PBMC is not predictive of the development of AIDS-NHL. EBV DNA was also detectable in serum at some time points but at a lower level",

author = "\{van Baarle\}, Debbie and Wolthers, \{Katja C.\} and Egbert Hovenkamp and Niesters, \{Hubert G. M.\} and Osterhaus, \{Albert D. M. E.\} and Frank Miedema and \{van Oers\}, \{Marinus H. J.\}",

year = "2002",

doi = "10.1086/341460",

language = "English",

volume = "186",

pages = "405--409",

journal = "Journal of infectious diseases",

issn = "0022-1899",

publisher = "Oxford University Press",

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TY - JOUR

T1 - Absolute level of Epstein-Barr virus DNA in human immunodeficiency virus type 1 infection is not predictive of AIDS-related non-Hodgkin lymphoma

AU - van Baarle, Debbie

AU - Wolthers, Katja C.

AU - Hovenkamp, Egbert

AU - Niesters, Hubert G. M.

AU - Osterhaus, Albert D. M. E.

AU - Miedema, Frank

AU - van Oers, Marinus H. J.

PY - 2002

Y1 - 2002

N2 - To study whether Epstein-Barr virus (EBV) load can be used to predict the occurrence of acquired immunodeficiency syndrome-related non-Hodgkin lymphoma (AIDS-NHL), we determined EBV load longitudinally for individuals infected with human immunodeficiency virus type 1. EBV load in peripheral blood mononuclear cells (PBMC) was high and displayed considerable fluctuations over time, indicating that absolute EBV load in PBMC is not predictive of the development of AIDS-NHL. EBV DNA was also detectable in serum at some time points but at a lower level

AB - To study whether Epstein-Barr virus (EBV) load can be used to predict the occurrence of acquired immunodeficiency syndrome-related non-Hodgkin lymphoma (AIDS-NHL), we determined EBV load longitudinally for individuals infected with human immunodeficiency virus type 1. EBV load in peripheral blood mononuclear cells (PBMC) was high and displayed considerable fluctuations over time, indicating that absolute EBV load in PBMC is not predictive of the development of AIDS-NHL. EBV DNA was also detectable in serum at some time points but at a lower level

U2 - 10.1086/341460

DO - 10.1086/341460

M3 - Article

C2 - 12134237

SN - 0022-1899

VL - 186

SP - 405

EP - 409

JO - Journal of infectious diseases

JF - Journal of infectious diseases

IS - 3

ER -

Absolute level of Epstein-Barr virus DNA in human immunodeficiency virus type 1 infection is not predictive of AIDS-related non-Hodgkin lymphoma

Abstract

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