AAV9-Mediated TNPO3 Overexpression in the Heart Rescues RBM20 Cardiomyopathy in Mice

Julia Kornienko; Laura Schraft; Kai Fenzl; Maarten M. G. van den Hoogenhof; Lars M. Steinmetz

doi:10.1161/CIRCULATIONAHA.124.072766

AAV9-Mediated TNPO3 Overexpression in the Heart Rescues RBM20 Cardiomyopathy in Mice

Julia Kornienko
, Laura Schraft
, Kai Fenzl
, Maarten M. G. van den Hoogenhof
, Lars M. Steinmetz^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Original language	English
Pages (from-to)	739-742
Number of pages	4
Journal	Circulation
Volume	152
Issue number	10
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.124.072766
Publication status	Published - 9 Sept 2025

Keywords

cardiomyopathies
genes
genetic therapy
mice
precision medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1161/CIRCULATIONAHA.124.072766

Aav9-mediated-tnpo3-overexpression-in-the-heart-rescues-rbm20-cardiomyopathy-in-mice.pdfFinal published version, 1.51 MBLicence: CC BY

Cite this

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title = "AAV9-Mediated TNPO3 Overexpression in the Heart Rescues RBM20 Cardiomyopathy in Mice",

keywords = "cardiomyopathies, genes, genetic therapy, mice, precision medicine",

author = "Julia Kornienko and Laura Schraft and Kai Fenzl and \{van den Hoogenhof\}, \{Maarten M. G.\} and Steinmetz, \{Lars M.\}",

year = "2025",

month = sep,

day = "9",

doi = "10.1161/CIRCULATIONAHA.124.072766",

language = "English",

volume = "152",

pages = "739--742",

journal = "Circulation",

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publisher = "Lippincott Williams and Wilkins",

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T1 - AAV9-Mediated TNPO3 Overexpression in the Heart Rescues RBM20 Cardiomyopathy in Mice

AU - Kornienko, Julia

AU - Schraft, Laura

AU - Fenzl, Kai

AU - van den Hoogenhof, Maarten M. G.

AU - Steinmetz, Lars M.

PY - 2025/9/9

Y1 - 2025/9/9

KW - cardiomyopathies

KW - genes

KW - genetic therapy

KW - mice

KW - precision medicine

UR - https://www.scopus.com/pages/publications/105015377091

U2 - 10.1161/CIRCULATIONAHA.124.072766

DO - 10.1161/CIRCULATIONAHA.124.072766

M3 - Article

C2 - 40920839

SN - 0009-7322

VL - 152

SP - 739

EP - 742

JO - Circulation

JF - Circulation

IS - 10

ER -

AAV9-Mediated TNPO3 Overexpression in the Heart Rescues RBM20 Cardiomyopathy in Mice

Keywords

UN SDGs

Access to Document

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