A sexually dimorphic nucleus in the human brain

D. F. Swaab; E. Fliers

doi:10.1126/science.3992248

A sexually dimorphic nucleus in the human brain

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Abstract

A sexually dimorphic cell group is described in the preoptic area of the human hypothalamus. Morphometric analysis revealed that the volume of this nucleus is 2.5 +/- 0.6 times (mean +/- standard error of the mean) as large in men as in women, and contains 2.2 +/- 0.5 times as many cells. Between the ages of 10 and 93 years, the nucleus decreases greatly in volume and in cell number. Although no function has yet been established for this nucleus, it is located within an area that is essential for gonadotropin release and sexual behavior in other mammals

Original language	English
Pages (from-to)	1112-1115
Journal	Science
Volume	228
Issue number	4703
DOIs	https://doi.org/10.1126/science.3992248
Publication status	Published - 1985

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10.1126/science.3992248

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title = "A sexually dimorphic nucleus in the human brain",

abstract = "A sexually dimorphic cell group is described in the preoptic area of the human hypothalamus. Morphometric analysis revealed that the volume of this nucleus is 2.5 +/- 0.6 times (mean +/- standard error of the mean) as large in men as in women, and contains 2.2 +/- 0.5 times as many cells. Between the ages of 10 and 93 years, the nucleus decreases greatly in volume and in cell number. Although no function has yet been established for this nucleus, it is located within an area that is essential for gonadotropin release and sexual behavior in other mammals",

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year = "1985",

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AU - Fliers, E.

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N2 - A sexually dimorphic cell group is described in the preoptic area of the human hypothalamus. Morphometric analysis revealed that the volume of this nucleus is 2.5 +/- 0.6 times (mean +/- standard error of the mean) as large in men as in women, and contains 2.2 +/- 0.5 times as many cells. Between the ages of 10 and 93 years, the nucleus decreases greatly in volume and in cell number. Although no function has yet been established for this nucleus, it is located within an area that is essential for gonadotropin release and sexual behavior in other mammals

AB - A sexually dimorphic cell group is described in the preoptic area of the human hypothalamus. Morphometric analysis revealed that the volume of this nucleus is 2.5 +/- 0.6 times (mean +/- standard error of the mean) as large in men as in women, and contains 2.2 +/- 0.5 times as many cells. Between the ages of 10 and 93 years, the nucleus decreases greatly in volume and in cell number. Although no function has yet been established for this nucleus, it is located within an area that is essential for gonadotropin release and sexual behavior in other mammals

U2 - 10.1126/science.3992248

DO - 10.1126/science.3992248

M3 - Article

C2 - 3992248

SN - 0036-8075

VL - 228

SP - 1112

EP - 1115

JO - Science

JF - Science

IS - 4703

ER -

A sexually dimorphic nucleus in the human brain

Abstract

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