A role for secretory phospholipase A2 and C-reactive protein in the removal of injured cells

C. Erik Hack; Gert Jan Wolbink; Caspar Schalkwijk; Han Speijer; Willem Th Hermens; Henk D. Van Den Bosch

doi:10.1016/S0167-5699(97)01002-5

A role for secretory phospholipase A₂ and C-reactive protein in the removal of injured cells

C. Erik Hack^*
, Gert Jan Wolbink
, Caspar Schalkwijk
, Han Speijer
, Willem Th Hermens
, Henk D. Van Den Bosch

^*Corresponding author for this work

University of Amsterdam
Amsterdam UMC - Vrije Universiteit Amsterdam
Utrecht University
Maastricht University

Research output: Contribution to journal › Comment/Letter to the editor › Academic

Abstract

The acute phase response is initiated in response to infection or physical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and colleagues suggest that the combined actions of two of these acute phase proteins, secretory phospholipase A₂ and C-reactive protein, may serve to promote phagocytosis of injured cells and tissue debris, thereby enhancing inflammation and tissue damage.

Original language	English
Pages (from-to)	111-115
Number of pages	5
Journal	Immunology today
Volume	18
Issue number	3
DOIs	https://doi.org/10.1016/S0167-5699(97)01002-5
Publication status	Published - Mar 1997

Access to Document

10.1016/S0167-5699(97)01002-5

Cite this

@article{054496e9a23f4c16b2ab6359c73c98c7,

title = "A role for secretory phospholipase A2 and C-reactive protein in the removal of injured cells",

abstract = "The acute phase response is initiated in response to infection or physical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and colleagues suggest that the combined actions of two of these acute phase proteins, secretory phospholipase A2 and C-reactive protein, may serve to promote phagocytosis of injured cells and tissue debris, thereby enhancing inflammation and tissue damage.",

author = "Hack, \{C. Erik\} and Wolbink, \{Gert Jan\} and Caspar Schalkwijk and Han Speijer and Hermens, \{Willem Th\} and \{Van Den Bosch\}, \{Henk D.\}",

year = "1997",

month = mar,

doi = "10.1016/S0167-5699(97)01002-5",

language = "English",

volume = "18",

pages = "111--115",

journal = "Immunology today",

issn = "0167-5699",

publisher = "Elsevier BV",

number = "3",

}

TY - JOUR

T1 - A role for secretory phospholipase A2 and C-reactive protein in the removal of injured cells

AU - Hack, C. Erik

AU - Wolbink, Gert Jan

AU - Schalkwijk, Caspar

AU - Speijer, Han

AU - Hermens, Willem Th

AU - Van Den Bosch, Henk D.

PY - 1997/3

Y1 - 1997/3

N2 - The acute phase response is initiated in response to infection or physical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and colleagues suggest that the combined actions of two of these acute phase proteins, secretory phospholipase A2 and C-reactive protein, may serve to promote phagocytosis of injured cells and tissue debris, thereby enhancing inflammation and tissue damage.

AB - The acute phase response is initiated in response to infection or physical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and colleagues suggest that the combined actions of two of these acute phase proteins, secretory phospholipase A2 and C-reactive protein, may serve to promote phagocytosis of injured cells and tissue debris, thereby enhancing inflammation and tissue damage.

UR - https://www.scopus.com/pages/publications/0031106565

U2 - 10.1016/S0167-5699(97)01002-5

DO - 10.1016/S0167-5699(97)01002-5

M3 - Comment/Letter to the editor

C2 - 9078682

SN - 0167-5699

VL - 18

SP - 111

EP - 115

JO - Immunology today

JF - Immunology today

IS - 3

ER -

A role for secretory phospholipase A₂ and C-reactive protein in the removal of injured cells

Abstract

Access to Document

Other files and links

Fingerprint

Cite this