A novel four-component reaction for the synthesis of functionalised dihydropyrimidines

Danielle J. Vugts; Helen Jansen; Rob F. Schmitz; Romano V.A. Orru

doi:10.1039/b308243a

A novel four-component reaction for the synthesis of functionalised dihydropyrimidines

Danielle J. Vugts
, Helen Jansen
, Rob F. Schmitz
, Romano V.A. Orru^*

^*Corresponding author for this work

Vrije Universiteit Amsterdam

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In a multi-component reaction (MCR) of a phosphonate, nitriles, aldehydes and isocyanates, N3-functionalised dihydropyrimidines can be synthesised efficiently via a Horner-Emmons/aza Diels-Alder pathway.

Original language	English
Pages (from-to)	2594-2595
Number of pages	2
Journal	Chemical Communications
Volume	3
Issue number	20
DOIs	https://doi.org/10.1039/b308243a
Publication status	Published - 2003

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title = "A novel four-component reaction for the synthesis of functionalised dihydropyrimidines",

abstract = "In a multi-component reaction (MCR) of a phosphonate, nitriles, aldehydes and isocyanates, N3-functionalised dihydropyrimidines can be synthesised efficiently via a Horner-Emmons/aza Diels-Alder pathway.",

author = "Vugts, \{Danielle J.\} and Helen Jansen and Schmitz, \{Rob F.\} and Orru, \{Romano V.A.\}",

year = "2003",

doi = "10.1039/b308243a",

language = "English",

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journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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AU - Vugts, Danielle J.

AU - Jansen, Helen

AU - Schmitz, Rob F.

AU - Orru, Romano V.A.

PY - 2003

Y1 - 2003

N2 - In a multi-component reaction (MCR) of a phosphonate, nitriles, aldehydes and isocyanates, N3-functionalised dihydropyrimidines can be synthesised efficiently via a Horner-Emmons/aza Diels-Alder pathway.

AB - In a multi-component reaction (MCR) of a phosphonate, nitriles, aldehydes and isocyanates, N3-functionalised dihydropyrimidines can be synthesised efficiently via a Horner-Emmons/aza Diels-Alder pathway.

UR - https://www.scopus.com/pages/publications/0142156024

U2 - 10.1039/b308243a

DO - 10.1039/b308243a

M3 - Article

SN - 1359-7345

VL - 3

SP - 2594

EP - 2595

JO - Chemical Communications

JF - Chemical Communications

IS - 20

ER -

A novel four-component reaction for the synthesis of functionalised dihydropyrimidines

Abstract

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