25-OH Vitamin D concentrations measured by LC-MS/MS are equivalent in serum and EDTA plasma

Lisa N. van der Vorm; Caroline le Goff; Stéphanie Peeters; Konstantinos Makris; Etienne Cavalier; Annemieke C. Heijboer

doi:10.1016/j.steroids.2022.109096

25-OH Vitamin D concentrations measured by LC-MS/MS are equivalent in serum and EDTA plasma

Lisa N. van der Vorm
, Caroline le Goff
, Stéphanie Peeters
, Konstantinos Makris
, Etienne Cavalier
, Annemieke C. Heijboer^*

^*Corresponding author for this work

Amsterdam UMC - University of Amsterdam
Amsterdam University Medical Centers
University of Liege
General Hospital of Athens
Athens University Medical School
National and Kapodistrian University of Athens
University of Amsterdam

Research output: Contribution to journal › Comment/Letter to the editor › Academic

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Abstract

In contrast to a recent study reporting an unexpected significant difference for total 25-hydroxyvitamin D (25(OH)D) between serum and EDTA plasma, we demonstrate that concentrations of total 25(OH)D, 25(OH)D2, 25(OH)D3 and 24,25(OH)2D3 do not differ between matched serum and EDTA plasma samples, using two well-characterized LC-MS/MS methods.

Original language	English
Article number	109096
Journal	Steroids
Volume	187
DOIs	https://doi.org/10.1016/j.steroids.2022.109096
Publication status	Published - 1 Nov 2022

Keywords

25(OH)D
LC-MS/MS
Plasma
Serum
Vitamin D

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10.1016/j.steroids.2022.109096

25-oh-vitamin-d-concentrations-measured-by-lc-msms-are-equivalent-in-serum-and-edta-plasma.pdfFinal published version, 475 KBLicence: Taverne

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@article{a8137a83c08f4a558415a7fa938f6f9d,

title = "25-OH Vitamin D concentrations measured by LC-MS/MS are equivalent in serum and EDTA plasma",

abstract = "In contrast to a recent study reporting an unexpected significant difference for total 25-hydroxyvitamin D (25(OH)D) between serum and EDTA plasma, we demonstrate that concentrations of total 25(OH)D, 25(OH)D2, 25(OH)D3 and 24,25(OH)2D3 do not differ between matched serum and EDTA plasma samples, using two well-characterized LC-MS/MS methods.",

keywords = "25(OH)D, LC-MS/MS, Plasma, Serum, Vitamin D",

author = "\{van der Vorm\}, \{Lisa N.\} and \{le Goff\}, Caroline and St{\'e}phanie Peeters and Konstantinos Makris and Etienne Cavalier and Heijboer, \{Annemieke C.\}",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",

year = "2022",

month = nov,

day = "1",

doi = "10.1016/j.steroids.2022.109096",

language = "English",

volume = "187",

journal = "Steroids",

issn = "0039-128X",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - 25-OH Vitamin D concentrations measured by LC-MS/MS are equivalent in serum and EDTA plasma

AU - van der Vorm, Lisa N.

AU - le Goff, Caroline

AU - Peeters, Stéphanie

AU - Makris, Konstantinos

AU - Cavalier, Etienne

AU - Heijboer, Annemieke C.

PY - 2022/11/1

Y1 - 2022/11/1

N2 - In contrast to a recent study reporting an unexpected significant difference for total 25-hydroxyvitamin D (25(OH)D) between serum and EDTA plasma, we demonstrate that concentrations of total 25(OH)D, 25(OH)D2, 25(OH)D3 and 24,25(OH)2D3 do not differ between matched serum and EDTA plasma samples, using two well-characterized LC-MS/MS methods.

AB - In contrast to a recent study reporting an unexpected significant difference for total 25-hydroxyvitamin D (25(OH)D) between serum and EDTA plasma, we demonstrate that concentrations of total 25(OH)D, 25(OH)D2, 25(OH)D3 and 24,25(OH)2D3 do not differ between matched serum and EDTA plasma samples, using two well-characterized LC-MS/MS methods.

KW - 25(OH)D

KW - LC-MS/MS

KW - Plasma

KW - Serum

KW - Vitamin D

UR - https://www.scopus.com/pages/publications/85135534189

U2 - 10.1016/j.steroids.2022.109096

DO - 10.1016/j.steroids.2022.109096

M3 - Comment/Letter to the editor

C2 - 35931233

SN - 0039-128X

VL - 187

JO - Steroids

JF - Steroids

M1 - 109096

ER -

25-OH Vitamin D concentrations measured by LC-MS/MS are equivalent in serum and EDTA plasma

Abstract

Keywords

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