Research output per year
Research output per year
Project Details
Description
BIGPROMISE is a prospective perioperative biobank and cohort study in high-risk surgical patients. It systematically collects clinical data and serial blood samples before and after surgery to enable biomarker discovery, phenotyping, and validation of risk prediction models.
The aim is to improve early detection and understanding of postoperative complications—particularly infection, cardiovascular events, and functional decline—and to translate these insights into personalized, biomarker-guided perioperative care and decision-making.
The aim is to improve early detection and understanding of postoperative complications—particularly infection, cardiovascular events, and functional decline—and to translate these insights into personalized, biomarker-guided perioperative care and decision-making.
| Acronym | BIGPROMISE |
|---|---|
| Status | Active |
| Effective start/end date | 08/10/2021 → … |
Collaborative partners
- Amsterdam UMC
- Amphia ziekenhuis (Joint applicant)
- St. Antonius Nieuwegein (Joint applicant) (lead)
- Roche Diagnostics International Ltd (Project partner)
Keywords
- postoperative complications
- risk stratification
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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Does postoperative plasma IL-6 improve early prediction of infection after pulmonary cancer surgery? A two-centre prospective study
Reniers, T., Noordzij, P. G., Veen, E. J., Hofman, E. F. N., Taselaar, A. M., Visser, W. A., van der Heiden, P., Boeckx, S., Emmen, J. M. A., Dijkstra, I. M., Cremer, O. L., Vernooij, L. M. & Rettig, T. C. D., 2025, In: PLoS ONE. 20, 6, p. e0326537Research output: Contribution to journal › Article › Academic › peer-review
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Improving Prediction of Postoperative Atrial Fibrillation After Cardiac Surgery Using Multiple Pathophysiological Biomarkers: A Prospective Double-Centre Study
Noordzij, P. G., Thio, M. S. Y., Reniers, T., Dijkstra, I., Mondelli, G., Langelaan, M., Ruven, H. J. T. & Rettig, T. C. D., 27 May 2025, In: Journal of clinical medicine. 14, 11Research output: Contribution to journal › Article › Academic › peer-review
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Is chronic inflammation a risk factor for perioperative myocardial injury or heart failure in pancreatic surgery patients?
Reniers, T., Rettig, T., van Zeggeren, L., Dijkstra, I., Prinsze, K., Molenaar, I., van Santvoort, H., Cremer, O., Vernooij, L. & Noordzij, P., Jun 2025, In: BJA Open. 14, p. 100417Research output: Contribution to journal › Article › Academic › peer-review
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Troponin in Surgical Pathways
Noordzij, P. (Speaker)
25 Jun 2026Activity: Talk or presentation › Invited talk › Academic
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Risk of perioperative myocardial injury after on-pump cardiac surgery: a predictive model
Noordzij, P. (Participant)
Mar 2026 → May 2026Activity: Educational contribution / Supervising student theses, products › Supervising student theses › Educational
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The Association Between Intraoperative Glucose Variability and Postoperative Infections Within 30 Days after Cardiothoracic Surgery
Noordzij, P. (Participant)
10 Jan 2025Activity: Educational contribution / Supervising student theses, products › Supervising student theses › Educational