The George M. Hahn Award is presented every other year to an investigator whose research has contributed in a significant way to new clinical applications in thermal therapy. This lecture is named in honor of Dr. George Hahn who led a highly productive clinical program grant at Stanford for many years and his fundamental work in the heat shock response and in how hyperthermia modifies chemotherapy sensitivity still stand today as foundational work. His highly productive career exemplifies the translational attributes of this award