Personal profile
Specialisation
2025 Directeur-bestuurder Alzheimer Nederland
2025 Endowed chair: Alzheimer onderzoek en impact, department of Epidemiology & Data Science
2021-2025: Scientific director Alzheimer center Amsterdam
2014-2025: Pasman chair: Determinants of cognitive decline and dementia.
Background in neuropsychology and clinical epidemiology.
Research interests
2025: My interest increasingly focuses on how we make sure that results of research actually make an impact on society and healthcare.
2004 - 2025 Research of Alzheimer center Amsterdam works towards personalized medicine for Alzheimer's disease and other causes of dementia, with a focus on early onset dementia. Our research lines (1) finding the origin, (2) diagnosis & prognosis, (3) intervention & prevention.
Education/Academic qualification
Basis Kwalificatie Onderwijs (BKO), VUmc
Award Date: 26 Nov 2012
External positions
Executive director, Alzheimer Nederland, Amersfoort, Netherlands
1 Nov 2025 → …
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Collaborations and top research areas from the last five years
Research output
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Autonomic dysfunction and hypothalamic atrophy in frontotemporal dementia and primary psychiatric disorders
Timar, Y. S. S., van Engelen, M. P. E., Venkatraghavan, V., Billot, B., Fieldhouse, J. L. P., van't Hooft, J. J., de Boer, S. C. M., Koevoets, C. S., Hartog, L. W., Groot, C., Oudega, M. L., Vijverberg, J. G. B., van der Flier, W. M., Barkhof, F. & Pijnenburg, Y. A. L., 1 Jan 2026, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 18, 1, e70284.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Downloads (Pure) -
Federated Fine-Tuning of SAM-Med3D for MRI-Based Dementia Classification
Mouheb, K., Elbatel, M., Papma, J., Biessels, G. J., Claassen, J., Middelkoop, H., van Munster, B., van der Flier, W., Ramakers, I., Klein, S. & Bron, E. E., 2026, Bridging Regulatory Science and Medical Imaging Evaluation; and Distributed, Collaborative, and Federated Learning - 1st International Workshop, BRIDGE 2025, and 6th International Workshop, DeCaF 2025, Held in Conjunction with MICCAI 2025, Proceedings. Zamzmi, G., Reinke, A., Samala, R., Jiang, M., Li, X., Roth, H., Sidulova, M., Kooi, T., Albarqouni, S., Bakas, S. & Rieke, N. (eds.). Springer Science and Business Media Deutschland GmbH, Vol. 16135 LNCS. p. 69-79 11 p. (Lecture Notes in Computer Science; vol. 16135 LNCS).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Open AccessFile29 Downloads (Pure) -
Individualized prediction of clinical progression to dementia using plasma biomarkers in non-demented elderly
Honey, M. I. J., van Maurik, I. S., van Harten, A. C., Gouda, M., van Leeuwenstijn, M., Mank, A., Trieu, C., Bouteloup, V., Chêne, G., Pellegrin, I., Dufouil, C., Doecke, J. D., Fowler, C. J., Masters, C. L., Pijnenburg, Y., Wilson, D., van der Flier, W. M., Teunissen, C. E. & Verberk, I. M. W., 1 Dec 2026, In: Alzheimer's Research and Therapy. 18, 1, 4.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile20 Downloads (Pure) -
The relationship between cognitive screeners and everyday functioning in amyloid-positive participants from the Amsterdam Dementia Cohort
van der Putten-Toorenburg, A., Butterbrod, E., Schalet, B. D., van der Veere, P. J., Tewolde, M. E., Postema, M. C., van de Giessen, E., Teunissen, C. E., van Harten, A. C., van der Flier, W. M. & Sikkes, S. A. M., 1 Jan 2026, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 18, 1, e70233.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile26 Downloads (Pure) -
ABIDEing with automated cerebrospinal fluid assays: update of an MCI to dementia prediction model
van der Veere, P. J., van Harten, A. C., van Maurik, I. S., Teunissen, C. E., Barkhof, F., Vos, S. J. B., Frölich, L., Kornhuber, J., Wiltfang, J., Maier, W., Peters, O., Rüther, E., Frisoni, G. B., Spiru, L., Freund-Levi, Y., Wallin, Å. K., Hampel, H., Tsolaki, M., Kłoszewska, I. & Mecocci, P. & 18 others, , 1 Dec 2025, In: Alzheimer s & dementia. 21, p. e108352Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Downloads (Pure)
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Global Dementia Advisory Board Meeting
van der Flier, W. (Consultant)
Dec 2025Activity: Consultancy › Academic
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Consultancy on AI project
van der Flier, W. (Consultant)
15 Apr 2025 → 31 Oct 2025Activity: Consultancy › Academic
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From bench to bedside. New approaches in Alzheimer’s and Parkinson’s disease
van der Flier, W. (Speaker)
4 Apr 2025Activity: Talk or presentation › Oral presentation › Academic
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Advisory board on Epidemiology Study in Preclinical AD
van der Flier, W. (Consultant)
1 Apr 2025Activity: Consultancy › Academic
Press/Media
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Zo wordt onderzocht hoe alzheimer zich vóór dementie ontwikkelt
21/09/2024
1 Media contribution
Press/Media: Press / Media
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Datasets
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Additional file 3 of CSF proteins of inflammation, proteolysis and lipid transport define preclinical AD and progression to AD dementia in cognitively unimpaired individuals
Del Campo, M. (Contributor), Quesada, C. (Creator), Vermunt, L. (Creator), Peeters, C. F. W. (Creator), Hok-A-Hin, Y. S. (Creator), Trieu, C. (Creator), Braber, A. D. (Creator), Verberk, I. M. W. (Creator), Visser, P. J. (Creator), Tijms, B. M. (Creator), van der Flier, W. M. (Creator) & Teunissen, C. E. (Creator), Figshare, 2024
DOI: 10.6084/m9.figshare.27644845, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_CSF_proteins_of_inflammation_proteolysis_and_lipid_transport_define_preclinical_AD_and_progression_to_AD_dementia_in_cognitively_unimpaired_individuals/27644845
Dataset
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Additional file 2 of CSF proteins of inflammation, proteolysis and lipid transport define preclinical AD and progression to AD dementia in cognitively unimpaired individuals
Del Campo, M. (Contributor), Quesada, C. (Creator), Vermunt, L. (Creator), Peeters, C. F. W. (Creator), Hok-A-Hin, Y. S. (Creator), Trieu, C. (Creator), Braber, A. D. (Creator), Verberk, I. M. W. (Creator), Visser, P. J. (Creator), Tijms, B. M. (Creator), van der Flier, W. M. (Creator) & Teunissen, C. E. (Creator), Figshare, 2024
DOI: 10.6084/m9.figshare.27644842, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_CSF_proteins_of_inflammation_proteolysis_and_lipid_transport_define_preclinical_AD_and_progression_to_AD_dementia_in_cognitively_unimpaired_individuals/27644842
Dataset
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Additional file 2 of CSF proteins of inflammation, proteolysis and lipid transport define preclinical AD and progression to AD dementia in cognitively unimpaired individuals
Del Campo, M. (Contributor), Quesada, C. (Creator), Vermunt, L. (Creator), Peeters, C. F. W. (Creator), Hok-A-Hin, Y. S. (Creator), Trieu, C. (Creator), Braber, A. D. (Creator), Verberk, I. M. W. (Creator), Visser, P. J. (Creator), Tijms, B. M. (Creator), van der Flier, W. M. (Creator) & Teunissen, C. E. (Creator), Figshare, 2024
DOI: 10.6084/m9.figshare.27644842.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_CSF_proteins_of_inflammation_proteolysis_and_lipid_transport_define_preclinical_AD_and_progression_to_AD_dementia_in_cognitively_unimpaired_individuals/27644842/1
Dataset