Personal profile
Research interests
Biomarkers
Sepsis
Pneumonia (community acquired, hospital acquired and ventilator associated)
Gut microbiome
Infection and immunity
Specialisation
Host response in pneumonia-derived sepsis
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Diagnostic accuracy of ultra-low-dose chest CT vs chest X-ray for acute non-traumatic pulmonary diseases
Kanglie, M. M. N. P., van den Berk, I. A. H., van Engelen, T. S. R., Bipat, S. & on behalf of the OPTIMACT study group, 1 Aug 2025, In: European radiology. 35, 8, p. 4836-4845 10 p.Research output: Contribution to journal › Article › Academic › peer-review
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Effect of the gut microbiota-derived tryptophan metabolite indole-3-acetic acid in pneumonia
Kullberg, R. F. J., van Linge, C. C. A., Haak, B. W., Paul, P. S., Butler, J. M., Wolff, N., van Engelen, T. S. R., Sikkens, J. J., Bomers, M. K., Lefèvre, A., Cremer, O. L., Roelofs, J. J. T. H., Sovran, B., van den Wijngaard, R., de Vos, A. F., de Jonge, W. J., van der Poll, T. & Wiersinga, W. J., Dec 2025, In: Nature communications. 16, 1, p. 8565 8565.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile26 Downloads (Pure) -
Pathogen-specific host response in critically ill patients with blood stream infections: a nested case–control study
Butler, J. M., Peters-Sengers, H., Reijnders, T. D. Y., van Engelen, T. S. R., Uhel, F., van Vught, L. A., Schultz, M. J., Laterre, P.-F., François, B., Sánchez-García, M., Lombardo, E., Sweeney, T. E., Bonten, M. J., Wiersinga, W. J., Sampson, D., Bolero, L. C., Yager, T., Cremer, O. L., Scicluna, B. P. & van der Poll, T., 1 Jul 2025, In: EBioMedicine. 117, 105799.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile31 Downloads (Pure) -
Pneumonia: Pathogenesis, biomarkers and clinical implications
van Engelen, T. S. R., 2025, 333 p.Research output: PhD Thesis › Phd-Thesis - Research and graduation internal
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The blood transcriptional response in patients developing intensive care unit-acquired pneumonia
de Brabander, J., Michels, E. H. A., Butler, J. M., Reijnders, T. D. Y., van Engelen, T. S. R., Leite, G. G. F., Paling, F. P., Klarenbeek, A. M., Sie, D. L. S., Boyer, R. E., Sweeney, T. E., Bonten, M. J. M., Timbermont, L., Malhotra-Kumar, S., Kluytmans, J. A. J. W., Peters-Sengers, H. & ASPIRE-ICU study team, 2025, In: European respiratory journal. 65, 4, 2400592.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile35 Downloads (Pure)