Research output per year
Research output per year
Personal profile
Research interests
My research focuses on leveraging large-scale genetic and multi-omic data to understand cardiovascular diseases. Engrained within the Experimental Cardiology Department and the extended group of prof. Connie Bezzina, I study the genetic mechanisms of cardiomyopathies, atrial fibrillation, and various other cardiovascular disorders.
Our group creates and applies advanced statistical approaches to i) perform genetic association analyses to discover risk variants and genes, ii) to create multi-omic risk prediction models, and iii) to dissect the biological mechanisms underlying cardiovascular disorders.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Visiting Scientist, Broad Institute of MIT and Harvard
25 Oct 2024 → …
PhD Candidate, Broad Institute of MIT and Harvard
11 Jul 2022 → 24 Oct 2024
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Bi-allelic variants in POPDC2 cause an autosomal recessive syndrome presenting with cardiac conduction defects and hypertrophic cardiomyopathy
Nicastro, M., Vermeer, A. M. C., Postema, P. G., Tadros, R., Bowling, F. Z., Aegisdottir, H. M., Tragante, V., Mach, L., Postma, A. V., Lodder, E. M., van Duijvenboden, K., Zwart, R., Beekman, L., Wu, L., Jurgens, S. J., van der Zwaag, P. A., Alders, M., Allouba, M., Aguib, Y. & Santome, J. L. & 51 others, , 3 Jul 2025, In: American journal of human genetics. 112, 7, p. 1681-1698 18 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Cardiomyopathy-Associated Gene Variants in Atrial Fibrillation
Wijdeveld, L. F. J. M., Ajufo, E., Challa, S. P., Rämö, J. T., Wang, X., Kany, S., Halford, J. L., Weng, L.-C., Choi, S. H., Aragam, K. G., van Tintelen, J. P., Brundel, B. J. J. M., Jurgens, S. J. & Ellinor, P. T., 11 Jun 2025, In: JAMA cardiology. 10, 6, p. 564-573 10 p.Research output: Contribution to journal › Article › Academic › peer-review
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Coagulation factor XII haploinsufficiency is protective against venous thromboembolism in a population-scale multidimensional analysis
Haj, A. K., Paul, D. S., Jurgens, S. J., Eswaran, H., Weng, L.-C., Ryu, J., Rodriguez Espada, A., Chaudhry, S., Feingold, L. M., Burke, K., Koyama, S., Wang, X., Francis, J., Choi, S. H., Mackman, N., Bergmeier, W., Burgin, A., Rämö, J. T., Ellinor, P. T. & Grover, S. P. & 1 others, , 1 Dec 2025, In: Nat. Commun.. 16, 1, 8176.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Evaluation of polygenic scores for hypertrophic cardiomyopathy in the general population and across clinical settings
Zheng, S. L., Jurgens, S. J., McGurk, K. A., Xu, X., Grace, C., Theotokis, P. I., Buchan, R. J., Francis, C., de Marvao, A., Curran, L., Bai, W., Pua, C. J., Tang, H. C., Jorda, P., van Slegtenhorst, M. A., Verhagen, J. M. A., Harper, A. R., Ormondroyd, E., Chin, C. W. L. & Ware, J. S. & 20 others, , Mar 2025, In: Nat. Genet.. 57, 3, p. 563-571 9 p., 3328.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Downloads (Pure) -
Genomic medicine for heart failure prediction in patients with atrial fibrillation
Wijdeveld, L. F. J. M. & Jurgens, S. J., 1 Jul 2025, In: Europace. 27, 7, euaf113.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access
Prizes
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Dutch Heart Foundation - Junior Clinical Scientist Fellowship Grant
Jurgens, S. (Recipient), Feb 2023
Prize › Academic