Personal profile
Research interests
My clinical and research interests lie within diabetes around large hormonal transitions (pregnancy, menopause) and diabetes technology as well as in-hospital glucose regulation.
My goal is to improve the health of women with diabetes during pregnancy and menopause through top clinical care, conducting clinical research with a focus on technology and training the empathic physician of the future.
Currently, I set up a nationwide registry for pregnant women with pregestational diabetes and map the current care paths for these women in the Netherlands (funded by Diabetesfonds). The goal is to be able to benchmark care and implement a national best care protocol.
Also I am workpackage leader of the diabetes research line within the MenoPause consortium (funded by NWO) looking at the effect of (peri)menopause on diabetes development and regulation within the HELIUS cohort as well as the type 1 and type 2 population through interventional studies.
Further, to improve in-hospital care we perform the GUIDE study (funded by ZonMw) comparing a basal-bolus to a sliding-scale insuline regimen in postoperative surgical patients with type 2 diabetes in the hospital and look at the effect on postoperative wound infections.
Specialisation
External positions
member of the board, Diabeteskamer
1 Dec 2024 → …
member (NIV), Platform Diabeteshulpmiddelen (NDF)
1 Jan 2020 → …
sounding board group for the update of diabetes guidelines, Dutch Association of Internal Medicine (NIV)
1 Jan 2019 → …
member, Programme Organising Committee of the Dutch Endocrine Meeting
1 Jan 2018 → 1 Mar 2025
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Perceived blood glucose regulation after menopause: a cross-sectional survey in women with type 1 diabetes in the Netherlands
MenoPause Consortium, Nov 2025, In: Diabetologia. 68, 11, p. 2499-2510 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Downloads (Pure) -
Effect of Postmenopausal Hormone Therapy on Glucose Regulation in Women With Type 1 or Type 2 Diabetes: A Systematic Review and Meta-analysis
Speksnijder, E. M., ten Noever de Brauw, G. V., Malekzadeh, A., Bisschop, P. H., Stenvers, D. J. & Siegelaar, S. E., 1 Oct 2023, In: Diabetes care. 46, 10, p. 1866-1875 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile39 Downloads (Pure) -
Sex-based disparities in perceived versus objective glycaemic control in type 1 diabetes: a cross-sectional cohort study
Fuhri Snethlage, C. M., Smeets, P., de Groen, P., Rampanelli, E., van Raalte, D. H., DeVries, J. H., Meijnikman, A. S., Siegelaar, S., de Galan, B. E., Roep, B. O., Nieuwdorp, M. & Hanssen, N. M. J., Sept 2025, In: Lancet. Diabetes and endocrinology. 13, 9, p. 739-741 3 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile14 Downloads (Pure) -
Comparing advanced hybrid closed loop therapy and standard insulin therapy in pregnant women with type 1 diabetes (CRISTAL): a parallel-group, open-label, randomised controlled trial
Benhalima, K., Beunen, K., van Wilder, N., Ballaux, D., Vanhaverbeke, G., Taes, Y., Aers, X.-P., Nobels, F., Marlier, J., Lee, D., Cuypers, J., Preumont, V., Siegelaar, S. E., Painter, R. C., Laenen, A., Gillard, P. & Mathieu, C., 1 Jun 2024, In: The Lancet Diabetes and Endocrinology. 12, 6, p. 390-403 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile67 Downloads (Pure) -
Effects of GLP-1 agonists and SGLT2 inhibitors during pregnancy and lactation on offspring outcomes: a systematic review of the evidence. a systematic review of the evidence
Muller, D. R. P., Malekzadeh, A., Holleman, F., Painter, R. C. & Siegelaar, S. E., 10 Oct 2023, In: Frontiers in endocrinology. 14, p. 1215356 1215356.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile41 Downloads (Pure)
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Diabetes en menopauze
Siegelaar, S. (Speaker)
16 Sept 2025Activity: Talk or presentation › Invited talk › Academic
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MiniMed™ 780G system provides equal performance in female users compared to males in all age groups from pre-puberty to menopause
Siegelaar, S. (Speaker)
Sept 2025Activity: Talk or presentation › Oral presentation › Academic
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Bridging the gender gap in diabetes care with the MiniMed™ 780G AID system
Siegelaar, S. (Speaker)
20 Mar 2025Activity: Talk or presentation › Invited talk › Professional
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Best practice & research. Clinical endocrinology & metabolism (Journal)
Siegelaar, S. (Reviewer)
Jan 2025 → …Activity: Publication peer-review and editorial work › Editorial activity
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Diabeteskamer (External organisation)
Siegelaar, S. (Member)
2024 → …Activity: Membership › Membership of board › Professional
Courses
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Professionele ontwikkeling - 3
Nieuwenhuijsen, K., Roossien, L. & van den Berg, J. 02/09/2024 → 23/06/2025
Course
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